[HTML][HTML] Dendritic cell subsets in cancer immunity and tumor antigen sensing
Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …
Tumor microenvironment signaling and therapeutics in cancer progression
Tumor development and metastasis are facilitated by the complex interactions between
cancer cells and their microenvironment, which comprises stromal cells and extracellular …
cancer cells and their microenvironment, which comprises stromal cells and extracellular …
[HTML][HTML] Enhancing immunotherapy response in melanoma: myeloid-derived suppressor cells as a therapeutic target
FGO Kurt, S Lasser, I Arkhypov, J Utikal… - The Journal of …, 2023 - Am Soc Clin Investig
Despite the remarkable success of immune checkpoint inhibitors (ICIs) in melanoma
treatment, resistance to them remains a substantial clinical challenge. Myeloid-derived …
treatment, resistance to them remains a substantial clinical challenge. Myeloid-derived …
[HTML][HTML] Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
[HTML][HTML] Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance
The tumor microenvironment represents a complex network, in which tumor cells not only
communicate with each other but also with stromal and immune cells. Current research has …
communicate with each other but also with stromal and immune cells. Current research has …
[HTML][HTML] Exosome-based cell-cell communication in the tumor microenvironment
J Maia, S Caja, MC Strano Moraes, N Couto… - Frontiers in cell and …, 2018 - frontiersin.org
Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …
communication between transformed and non-transformed cells. The milieu created by …
Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes
Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
[HTML][HTML] Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases
The administration of mesenchymal stem cells (MSCs) as a therapy for liver disease holds
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …
[HTML][HTML] The function and clinical application of extracellular vesicles in innate immune regulation
The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
Extracellular vesicles in cancer immune microenvironment and cancer immunotherapy
F Xie, X Zhou, M Fang, H Li, P Su, Y Tu… - Advanced …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are secreted by almost all cells. They contain proteins, lipids,
and nucleic acids which are delivered from the parent cells to the recipient cells. Thereby …
and nucleic acids which are delivered from the parent cells to the recipient cells. Thereby …