Perspectives on folate with special reference to epigenetics and neural tube defects

KR Gurugubelli, VB Ballambattu - Reproductive Toxicology, 2024 - Elsevier
Folate is a micronutrient essential for DNA synthesis, cell division, fetal growth and
development. Folate deficiency leads to genomic instability. Inadequate intake of folate …

Planar Cell Polarity Signaling: Coordinated Crosstalk for Cell Orientation

S Kacker, V Parsad, N Singh, D Hordiichuk… - Journal of …, 2024 - mdpi.com
The planar cell polarity (PCP) system is essential for positioning cells in 3D networks to
establish the proper morphogenesis, structure, and function of organs during embryonic …

Dolutegravir and Folic Acid Interaction during Neural System Development in Zebrafish Embryos

D Zizioli, E Quiros-Roldan, S Ferretti, L Mignani… - International Journal of …, 2024 - mdpi.com
Dolutegravir (DTG) is one of the most prescribed antiretroviral drugs for treating people with
HIV infection, including women of child-bearing potential or pregnant. Nonetheless …

Epigenetic regulation by TET1 in gene-environmental interactions influencing susceptibility to congenital malformations

BK van der Veer, L Chen, SC Tsaniras, W Brangers… - bioRxiv, 2024 - biorxiv.org
The etiology of neural tube defects (NTDs) involves complex gene-environmental
interactions. Folate is the largest modifier of NTD risk, but mechanisms remain unclear …

Surviving against the odds: exploring the clinical and radiological features of iniencephaly compatible with life. Illustrative case

H Kadri, M Dughly, MS Agha, R Abouharb… - … of Neurosurgery: Case …, 2024 - thejns.org
BACKGROUND Iniencephaly is a rare neural tube defect (NTD) characterized by deformities
in the occiput and inion, along with rachischisis in the cervical and thoracic spine, resulting …

Bioactive Self-Assembled Protein Nanosheets for Stem Cell-Based Biotechnologies

H Kanso - 2024 - qmro.qmul.ac.uk
Tissue and stem cell culture methods have been dominated by glass and plastic substrates
such as Tissue culture plastic. These solid substrates, although widely used, are associated …