Ferroptosis is a new form of regulated cell death (RCD) driven by iron-dependent lipid
peroxidation, which is morphologically and mechanistically distinct from other forms of RCD …

Hepatocellular carcinoma is the most prevalent form of primary liver cancer with a
multifactorial aetiology comprising genetic, environmental, and behavioural factors. Evading …

Palmitic acid (PA)-induced myocardial injury is considered a critical contributor to the
development of obesity and type 2 diabetes mellitus (T2DM)-related cardiomyopathy …

Iron species can participate in the Fenton or Fenton‐like reaction to generate oxidizing
species that can cause oxidative damages to biomolecules and induce oxidative stress in …

Coronary heart disease (CHD) is closely related to oxidative stress and inflammatory
response and is the most common cardiovascular disease (CVD). Iron is an essential …

Iron deficiency and iron overload are the most prevalent and opposite forms of dysregulated
iron metabolism that affect approximately 30 percent of the world population, in particularly …

The dose‐dependent cardiomyopathy of adriamycin (doxorubicin) limits its long‐term
clinical use, which is revealed as a consequence of cardiomyocyte ferroptosis. As a ferrous …

Rationale: Human pluripotent stem cell (hPSC)–derived cardiomyocytes exhibit the
properties of fetal cardiomyocytes, which limits their applications. Various methods have …

Ferroptosis is one type of programmed cell death discovered in recent years, which is
characterized by iron-dependent lipid peroxidation and participating in iron, lipid and …

Iron overload as a highly risk factor, can be found in almost all human chronic and common
diseases. Iron chelators are often used to treat iron overload; however, patient adherence to …