Hypertension and dyslipidemia: the two partners in endothelium-related crime

E Dąbrowska, K Narkiewicz - Current Atherosclerosis Reports, 2023 - Springer
Abstract Purpose of Review The goal of this article is to characterize the endothelium's role
in the development of hypertension and dyslipidemia and to point out promising therapeutic …

Omics approaches unveiling the biology of human atherosclerotic plaques

X Wu, H Zhang - The American Journal of Pathology, 2024 - Elsevier
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
buildup of plaques with the accumulation and transformation of lipids, immune cells …

Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition

F Eichelmann, M Prada, L Sellem, KG Jackson… - Nature Medicine, 2024 - nature.com
Current cardiometabolic disease prevention guidelines recommend increasing dietary
unsaturated fat intake while reducing saturated fats. Here we use lipidomics data from a …

Perspectives on the success of plasma lipidomics in cardiovascular drug discovery and future challenges

T Abrahams, SJ Nicholls - Expert Opinion on Drug Discovery, 2024 - Taylor & Francis
Introduction Plasma lipidomics has emerged as a powerful tool in cardiovascular drug
discovery by providing insights into disease mechanisms, identifying potential biomarkers …

Percentiles of predicted 10-year cardiovascular disease risk by sex and age in Brazil and their association with estimated risk of long-term atherosclerotic events

FY Cesena, G Generoso, IS Santos, BB Duncan… - Preventive …, 2023 - Elsevier
Objective Expressing the cardiovascular disease (CVD) risk in relation to peers may
complement the estimation of absolute CVD risk. We aimed to determine 10-year CVD risk …

Plasma lipidomics profiles highlight the associations of the dual antioxidant/pro-oxidant molecules sphingomyelin and phosphatidylcholine with subclinical …

L Sojo, E Santos-González, L Riera, A Aguilera… - Antioxidants, 2023 - mdpi.com
Here, we report on our study of plasma lipidomics profiles of patients with type 1 diabetes
(T1DM) and explore potential associations. One hundred and seven patients with T1DM …

[HTML][HTML] Plasma proteomics for prediction of subclinical coronary artery calcifications in primary prevention

P Royer, E Björnson, M Adiels, MB Álvez… - American Heart …, 2024 - Elsevier
Background and aims Recent developments in high-throughput proteomic technologies
enable the discovery of novel biomarkers of coronary atherosclerosis. The aims of this study …

Lipidomic-Based Algorithms Can Enhance Prediction of Obstructive Coronary Artery Disease

T Mouskeftara, O Deda, T Liapikos… - Journal of Proteome …, 2024 - ACS Publications
Lipidomics emerges as a promising research field with the potential to help in personalized
risk stratification and improve our understanding on the functional role of individual lipid …

Prediction models for major adverse cardiovascular events after percutaneous coronary intervention: a systematic review

W Deng, D Wang, Y Wan, S Lai, Y Ding… - Frontiers in …, 2024 - frontiersin.org
Background The number of models developed for predicting major adverse cardiovascular
events (MACE) in patients undergoing percutaneous coronary intervention (PCI) is …

Pro-Inflammatory Biomarkers and Progression of Atherosclerosis in Patients with Myocardial Infarction with Non-Obstructive Coronary Artery Disease: 1-Year Follow …

VV Ryabov, DA Vorobeva, IV Kologrivova… - Journal of Personalized …, 2023 - mdpi.com
The objective of our study was to evaluate the concentrations of pro-inflammatory
biomarkers in patients with acute myocardial infarction with non-obstructive coronary …