Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Temozolomide, procarbazine and nitrosoureas in the therapy of malignant gliomas: update of mechanisms, drug resistance and therapeutic implications

B Kaina - Journal of clinical medicine, 2023 - mdpi.com
The genotoxic methylating agents temozolomide (TMZ) and procarbazine and the
chloroethylating nitrosourea lomustine (CCNU) are part of the standard repertoire in the …

[HTML][HTML] Photodynamic therapy for glioblastoma: a light at the end of the tunnel

M Miretti, MAG Graglia, AI Suárez, CG Prucca - Journal of Photochemistry …, 2023 - Elsevier
Glioblastomas (GBM) are considered one of the most aggressive tumors of the central
nervous system. The standard treatment for GBM-diagnosed patients implies surgery …

MGMT in TMZ-based glioma therapy: multifaceted insights and clinical trial perspectives

R Shaw, M Basu, S Karmakar, MK Ghosh - Biochimica et Biophysica Acta …, 2024 - Elsevier
Temozolomide (TMZ) is the most preferred and approved chemotherapeutic drug for either
first-or second-line chemotherapy for glioma patients across the globe. In glioma patients …

Oncolytic zika virus: new option for glioblastoma treatment

C Zhou, Q Chen, Y Chen, CF Qin - DNA and Cell Biology, 2023 - liebertpub.com
Glioblastoma (GBM) is one of the most aggressive brain tumors and has a high recurrence
rate, and effective treatment is urgently needed. GBM stem cells (GSCs) contribute to GBM …

Exploring monocytes-macrophages in immune microenvironment of glioblastoma for the design of novel therapeutic strategies

MD Caverzán, L Beaugé, PM Oliveda… - Brain Sciences, 2023 - mdpi.com
Gliomas are primary malignant brain tumors. These tumors seem to be more and more
frequent, not only because of a true increase in their incidence, but also due to the increase …

Revolutionizing Glioblastoma Treatment: A Comprehensive Overview of Modern Therapeutic Approaches

K Sadowski, A Jażdżewska, J Kozłowski… - International Journal of …, 2024 - mdpi.com
Simple Summary Glioblastoma is one of the most dangerous tumors of the central nervous
system, and still cannot be fully overcome. We still mainly rely on standard treatments …

Electromagnetic Nature of Distant Interaction of the Atmospheric Pressure Helium Plasma Discharge Tube with Glioblastoma Cancer Cells

DB Zolotukhin, A Horkowitz… - ACS Applied Materials & …, 2024 - ACS Publications
Atmospheric pressure coaxial gaseous discharge tubes (DTs) with helium have
demonstrated potential for in vitro inactivation or sensitization of glioblastoma cancer cells …

Enhancing glioblastoma treatment through the integration of tumor-treating fields

K Szklener, M Bilski, K Nieoczym, D Mańdziuk… - Frontiers in …, 2023 - frontiersin.org
Glioblastoma (GBM) represents a significant therapeutic challenge due to its aggressive
nature. Tumor Treating Fields (TTFields) present a promising approach to GBM therapy. The …

Advanced tumor electric fields therapy: A review of innovative research and development and prospect of application in glioblastoma

J Lan, Y Liu, J Chen, H Liu, Y Feng… - CNS Neuroscience & …, 2024 - Wiley Online Library
Background Glioblastoma multiforme (GBM) is an aggressive malignant tumor with a high
mortality rate and is the most prevalent primary intracranial tumor that remains incurable …