[HTML][HTML] Recent advances in brain delivery of synthetic and natural nano therapeutics: Reviving hope for Alzheimer's disease patients

DS Nady, U Bakowsky, SA Fahmy - Journal of Drug Delivery Science and …, 2023 - Elsevier
As the globe's population increases, the incidences of Alzheimer's disease (AD) are steadily
increasing. AD represents the most common neurological disorder and constitutes 60–70 …

Recent Advances in Nanoformulations for Quercetin Delivery

EM Tomou, P Papakyriakopoulou, EM Saitani… - Pharmaceutics, 2023 - mdpi.com
Quercetin (QUE) is a flavonol that has recently received great attention from the research
community due to its important pharmacological properties. However, QUE's low solubility …

Phytochemical Interactions with Calmodulin and Critical Calmodulin Binding Proteins Involved in Amyloidogenesis in Alzheimer's Disease

DH O'Day - Biomolecules, 2023 - mdpi.com
An increasing number of plant-based herbal treatments, dietary supplements, medical foods
and nutraceuticals and their component phytochemicals are used as alternative treatments …

[HTML][HTML] Effects of aerobic exercise and dietary flavonoids on cognition: a systematic review and meta-analysis

DK Joseph, AFM Ludin, FW Ibrahim… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Introduction: Studies have shown that exercise increases angiogenesis and perfusion in the
hippocampus, activates neurogenesis in the dentate gyrus and increases synaptic plasticity …

Development, optimization, and evaluation of Empagliflozin nanoemulsion for the management of neuroinflammation associated Alzheimer's disease

NA Alhakamy, EA Aljehani, AB Abdel-Naim… - Journal of Drug Delivery …, 2024 - Elsevier
Alzheimer's disease (AD) is one of the most pervasive and progressive neurodegenerative
disorders. Recently, empagliflozin (EMPA) has been reported as a potent anti-inflammatory …

[HTML][HTML] Anti-SARS-CoV-2, antioxidant and immunomodulatory potential of dietary flavonol quercetin: Focus on molecular targets and clinical efficacy

B Dinda, M Dinda, S Dinda, PS Ghosh… - European Journal of …, 2023 - Elsevier
The current coronavirus disease 2019 (COVID-19) outbreak, caused by the infection of
SARS-CoV-2, seems to be a tough global challenge because of its highly contagious nature …

[HTML][HTML] Naringenin ameliorates Cyclophosphamide-induced nephrotoxicity in experimental model

NK Alaqeel, MT Al-Hariri - Saudi Journal of Biological Sciences, 2023 - Elsevier
Cyclophosphamide (CP) is widely described in the management of several nonneoplastic
and neoplastic disorders. Renal damage is the most reported toxic effect of CP in clinical …

Uses of Nanoemulsions in Pharmaceuticals Industries

AI Elshamy, WA El-Kashak, RF Taher… - Current Trends in Green …, 2023 - Springer
Nanoemulsions have attracted great attention in research, dosage form design and
pharmacotherapy. This is as a result of a number of attributes peculiar to nanoemulsions …

Polyherbal and Multimodal Treatments: Kaempferol-and Quercetin-Rich Herbs Alleviate Symptoms of Alzheimer's Disease

C Alexander, A Parsaee, M Vasefi - Biology, 2023 - mdpi.com
Simple Summary Despite the well-documented pathophysiology of Alzheimer's Disease
(AD), treatment options are limited in diversity and efficacy. Thus, the development of new …

Nanoformulations targeting Alzheimer's disease

D Kapoor, D Sharma, Y Pathak, BG Prajapati… - Alzheimer's Disease and …, 2024 - Elsevier
Nanotechnology plays pivotal role to solve the therapeutic and diagnostic challenges that
are associated various neurodegenerative diseases. The Alzheimer's disease (ADs) is one …