Long-term exercise from adolescence to adulthood reduces anxiety-and depression-like behaviors following maternal immune activation in offspring

S Rahimi, M Peeri, MA Azarbayjani, L Anoosheh… - Physiology & …, 2020 - Elsevier
Maternal immune activation is an environmental risk factor for the development of
neuropsychiatric disorders such as anxiety and depression later in life. There is an urgent …

Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy

M Zeraati, N Najdi, B Mosaferi, AA Salari - Behavioural brain research, 2021 - Elsevier
Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

Dual-enzymatically cross-linked gelatin hydrogel promotes neural differentiation and neurotrophin secretion of bone marrow-derived mesenchymal stem cells for …

J Li, D Zhang, S Guo, C Zhao, L Wang, S Ma… - International Journal of …, 2021 - Elsevier
Traumatic brain injury (TBI) is one of the most devastating nervous injuries. Neural tissue
engineering based on stem cells and bioactive scaffold is a promising but challenging …

[HTML][HTML] Tea saponins as natural emulsifiers and cryoprotectants to prepare silymarin nanoemulsion

M Deng, H Chen, L Xie, K Liu, X Zhang, X Li - Lwt, 2022 - Elsevier
Tea saponins (TS), a natural surfactant, are extracted from Camellia oleifera seed meal of
Camellia plants. Silymarin (SM) is a flavonoid compound with hepatoprotective effect, and its …

Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with …

S Naghibi, MS Joneydi, A Barzegari… - Physiology & …, 2021 - Elsevier
Alzheimer's disease (AD) is associated with increased depression-related behaviours.
Previous studies have reported a greater risk of AD and depression in women. In recent …

[HTML][HTML] Silymarin and Inflammation: Food for Thoughts

PF Surai, A Surai, K Earle-Payne - Antioxidants, 2024 - mdpi.com
Inflammation is a vital defense mechanism, creating hostile conditions for pathogens,
preventing the spread of tissue infection and repairing damaged tissues in humans and …

[HTML][HTML] Antidepressant-like potential of silymarin and silymarin-sertraline combination in mice: Highlighting effects on behaviour, oxidative stress, and …

AY Onaolapo, H Sulaiman, AT Olofinnade… - World Journal of …, 2022 - wjgnet.com
BACKGROUND Currently, there is increasing advocacy for the use of diet, dietary
supplements, and herbal remedies in depression management. AIM To determine the …

Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction

S Saral, A Topçu, M Alkanat, T Mercantepe… - Behavioural brain …, 2021 - Elsevier
It has been established that cisplatin causes neuronal damage and cognitive impairment.
However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with …

Melatonin treatment improves cognitive deficits by altering inflammatory and neurotrophic factors in the hippocampus of obese mice

S Mansouri, AA Salari, A Abedi, P Mohammadi… - Physiology & …, 2022 - Elsevier
Overweight and obesity are associated with an increased risk of developing dementia and
cognitive deficits. Neuroinflammation is one of the most important mechanisms behind …

Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus

S Saral, A Topçu, M Alkanat, T Mercantepe… - Journal of Chemical …, 2023 - Elsevier
Cisplatin is a drug used effectively in the treatment of malignant tumors. However, cisplatin
has many side effects, including cognitive impairment. Agomelatine, a synthetic melatonin …