Psoriasis is a chronic inflammatory disease characterised by sharply demarcated
erythematous and scaly skin lesions accompanied by systemic manifestations. Classified by …

COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

Mammalian cells autonomously activate hypoxia-inducible transcription factors (HIFs) to
ensure survival in low-oxygen environments. We report here that injury-induced hypoxia is …

Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory disorders of
the gastrointestinal tract. Accumulating evidence shows that the development of IBD is …

Pyoderma gangrenosum is a rare inflammatory skin disease classified within the group of
neutrophilic dermatoses and clinically characterized by painful, rapidly evolving cutaneous …

Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue
in the periodontal region. Although dysbiosis of the local microbial community initiates local …

Depression is one of the leading mental illnesses worldwide and lowers the quality of life of
many. According to WHO, about 5% of the worldwide population suffers from depression …

The immune system plays a critical role in protecting hosts from the invasion of organisms.
CD4 T cells, as a key component of the immune system, are central in orchestrating adaptive …

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that presents with rapidly
developing, painful skin ulcers hallmarked by undermined borders and peripheral erythema …