Signaling pathways involved in diabetic renal fibrosis
Y Zhang, D Jin, X Kang, R Zhou, Y Sun… - Frontiers in cell and …, 2021 - frontiersin.org
Diabetic kidney disease (DKD), as the most common complication of diabetes mellitus (DM),
is the major cause of end-stage renal disease (ESRD). Renal interstitial fibrosis is a crucial …
is the major cause of end-stage renal disease (ESRD). Renal interstitial fibrosis is a crucial …
A glimpse of the mechanisms related to renal fibrosis in diabetic nephropathy
LF Zeng, Y Xiao, L Sun - Renal Fibrosis: Mechanisms and Therapies, 2019 - Springer
Diabetic nephropathy (DN) is a common kidney disease in people with diabetes, which is
also a serious microvascular complication of diabetes and the main cause of end-stage …
also a serious microvascular complication of diabetes and the main cause of end-stage …
Relaxin as an anti-fibrotic treatment: Perspectives, challenges and future directions
CS Samuel, RG Bennett - Biochemical Pharmacology, 2022 - Elsevier
Fibrosis refers to the scarring and hardening of tissues, which results from a failed immune
system-coordinated wound healing response to chronic organ injury and which manifests …
system-coordinated wound healing response to chronic organ injury and which manifests …
Cellular phenotypic transitions in diabetic nephropathy: an update
Diabetic nephropathy (DN) is a major cause of morbidity and mortality in diabetes and is the
most common cause of end stage renal disease (ESRD). Renal fibrosis is the final …
most common cause of end stage renal disease (ESRD). Renal fibrosis is the final …
Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC‐1α Signaling in db/db Mice
S Hou, T Zhang, Y Li, F Guo… - Journal of diabetes …, 2017 - Wiley Online Library
Diabetic nephropathy (DN) is a major cause of end‐stage renal disease (ESRD).
Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production …
Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production …
Macrophage polarization in tissue fibrosis
H Yang, H Cheng, R Dai, L Shang, X Zhang, H Wen - PeerJ, 2023 - peerj.com
Fibrosis can occur in all major organs with relentless progress, ultimately leading to organ
failure and potentially death. Unfortunately, current clinical treatments cannot prevent or …
failure and potentially death. Unfortunately, current clinical treatments cannot prevent or …
Study of the Active Components and Molecular Mechanism of Tripterygium wilfordii in the Treatment of Diabetic Nephropathy
L Wang, Z Wang, Z Yang, K Yang… - Frontiers in Molecular …, 2021 - frontiersin.org
We aimed to explore the active ingredients and molecular mechanism of Tripterygium
wilfordii (TW) in the treatment of diabetic nephropathy (DN) through network pharmacology …
wilfordii (TW) in the treatment of diabetic nephropathy (DN) through network pharmacology …
[HTML][HTML] Prediction of the potential mechanism of triptolide in improving diabetic nephropathy by utilizing a network pharmacology and molecular docking approach
X An, D Fan, Z Yin, J Zhang, Y Zhou, R Tian… - Frontiers in Bioscience …, 2022 - imrpress.com
Background: Triptolide (TP) is a major active component of colquhounia root tablet, which
has been long been used in China to treat diabetic nephropathy (DN) due to its marked anti …
has been long been used in China to treat diabetic nephropathy (DN) due to its marked anti …
[HTML][HTML] Protective effects and microarray-based mechanism of sea cucumber hydrolysates against high-glucose induced nephrotoxicity in mouse glomerulus …
L Geng, J Han, J Zhou, Y Li, T Ming, Z Zhang, C Lu… - Journal of Future …, 2024 - Elsevier
Diabetic nephropathy (DN) is a common type of end-stage renal disease and glomerular
mesangial cells (GMCs) are widely used as a cell model for DN. This study firstly …
mesangial cells (GMCs) are widely used as a cell model for DN. This study firstly …
Colquhounia root tablet improves diabetic kidney disease by regulating epithelial-mesenchymal transition via the PTEN/PI3K/AKT pathway
D Ma, J Zhang, L Du, J Shi, Z Liu, J Qin… - Frontiers in …, 2024 - frontiersin.org
Background Diabetic kidney disease (DKD) is a severe microvascular complication of
diabetes mellitus that can lead to end-stage renal disease. Colquhounia root tablet (CRT) …
diabetes mellitus that can lead to end-stage renal disease. Colquhounia root tablet (CRT) …