Cell surface receptors, virus entry and tropism of primate lentiviruses

PR Clapham, Á McKnight - Journal of General Virology, 2002 - microbiologyresearch.org
Human immunodeficiency virus (HIV) exploits cell surface receptors to attach to and gain
entry into cells. The HIV envelope spike glycoprotein on the surface of virus particles binds …

[PDF][PDF] Human immunodeficiency virus (HIV)‐1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein‐1 expression …

AC Tuyama, F Hong, Y Saiman, C Wang, D Ozkok… - …, 2010 - Wiley Online Library
Patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV)
develop more rapid fibrosis than those infected with HCV only. In HIV/HCV‐coinfected …

Primary human immunodeficiency virus type 2 (HIV-2) isolates infect CD4-negative cells via CCR5 and CXCR4: comparison with HIV-1 and simian immunodeficiency …

JD Reeves, S Hibbitts, G Simmons, A McKnight… - Journal of …, 1999 - Am Soc Microbiol
Cell surface receptors exploited by human immunodeficiency virus (HIV) and simian
immunodeficiency virus (SIV) for infection are major determinants of tropism. HIV-1 usually …

[PDF][PDF] Endocytic entry of HIV-1

OT Fackler, BM Peterlin - Current Biology, 2000 - cell.com
Enveloped viruses enter target cells by membrane fusion or endocytosis. In the latter case,
fusion of the viral envelope is induced by the acidic pH of the endocytic vesicle [1]. As with …

HIV coreceptors, cell tropism and inhibition by chemokine receptor ligands

PR Clapham, JD Reeves, G Simmons… - Molecular membrane …, 1999 - Taylor & Francis
HIV is a persistent virus that survives and replicates despite an onslaught by the host's
immune system. A strategy for cell entry, requiring the use of two receptors, has evolved that …

Identification of a subset of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus strains able to exploit an alternative coreceptor …

SJ Willey, JD Reeves, R Hudson, K Miyake… - Journal of …, 2003 - Am Soc Microbiol
The chemokine receptors CCR5 and CXCR4 are the major coreceptors for human
immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). At least 12 other …

CD4-independent infection of HIV and SIV: implications for envelope conformation and cell tropism in vivo

J Bhattacharya, PJ Peters, PR Clapham - Aids, 2003 - journals.lww.com
The primate immunodeficiency viruses (HIV and SIV) are enveloped viruses that normally
require successive interactions with CD4 and a co-receptor to trigger the fusion of viral and …

Human Leydig cells are productively infected by some HIV-2 and SIV strains but not by HIV-1

S Willey, V Roulet, JD Reeves, ML Kergadallan… - Aids, 2003 - journals.lww.com
Objectives: With the use of highly active antiretroviral therapy, the identification of HIV
reservoirs within the body has become an important issue. However, the testis has been …

Synthesis of biotinylated glycoconjugates and their use in a novel ELISA for direct comparison of HIV-1 Gp120 recognition of GalCer and related carbohydrate …

KD McReynolds, MJ Hadd… - Bioconjugate …, 1999 - ACS Publications
As part of our program directed toward the design and synthesis of high-affinity ligands for
the GalCer-binding site on the HIV cell surface glycoprotein, gp120, we required a reliable …

Thermally induced phase separation in supported bilayers of glycosphingolipid and phospholipid mixtures

AW Szmodis, CD Blanchette, ML Longo, CA Orme… - …, 2010 - pubs.aip.org
The authors have studied microstructure evolution during thermally induced phase
separation in a class of binary supported lipid bilayers using a quantitative application of …