Psychotropic drug–related weight gain and its treatment

RS McIntyre, ATH Kwan, JD Rosenblat… - American Journal of …, 2024 - Am Psychiatric Assoc
Psychotropic drug–related weight gain (PDWG) is a common occurrence and is highly
associated with non-initiation, discontinuation, and dissatisfaction with psychiatric drugs …

[HTML][HTML] Glucagon-like Peptide 1 Agonist and Effects on Reward Behaviour: A Systematic Review

S Badulescu, A Tabassum, GH Le, S Wong, L Phan… - Physiology & …, 2024 - Elsevier
Introduction The roles of metabolic signals, including Glucagon-like peptide 1 (GLP-1), have
been implicated in multiple domains outside metabolic regulation. There is a growing …

[HTML][HTML] G protein-coupled receptor-biased signaling: potential drug discovery to facilitate treatment of metabolic diseases

S Shen, Q Liao, L Gu, Y Zhu, Y Liu, X Zhang… - Acta Materia …, 2024 - scienceopen.com
G protein-coupled receptors (GPCRs) are important, potential drug targets for the treatment
of metabolic disorders, such as obesity. GPCRs crosstalk with several transducers, including …

Social media as pharmacovigilance: The potential for patient reports to inform clinical research on glucagon-like peptide 1 (GLP-1) receptor agonists for substance …

MP Bremmer, CS Hendershot - Journal of Studies on Alcohol and Drugs, 2024 - jsad.com
The surge in popularity of semaglutide (Ozempic, Wegovy, Rybelsus) and other glucagon-
like-peptide 1 (GLP-1) receptor agonists has been accompanied by widespread reports of …

Poly-agonist pharmacotherapies for metabolic diseases: hopes and new challenges

C Allard, D Cota, C Quarta - Drugs, 2024 - Springer
The use of glucagon-like peptide-1 (GLP-1) receptor-based multi-agonists in the treatment of
type 2 diabetes and obesity holds great promise for improving glycaemic control and weight …

[HTML][HTML] Multi-omics strategy reveals that Cordyceps sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy …

L Chen, T Yang, J Wu, G Cheng, M Zhao… - Acta Materia …, 2024 - scienceopen.com
Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …

[HTML][HTML] Glucagon-like peptide-1 receptor: mechanisms and advances in therapy

Z Zheng, Y Zong, Y Ma, Y Tian, Y Pang… - … and Targeted Therapy, 2024 - nature.com
Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital
component of the G protein-coupled receptor (GPCR) family and is found primarily on the …

How are overweight and obesity associated with reinforcement learning deficits? A systematic review

G Weydmann, PM Miguel, N Hakim, L Dube… - Appetite, 2023 - Elsevier
Reinforcement learning (RL) refers to the ability to learn stimulus-response or response-
outcome associations relevant to the acquisition of behavioral repertoire and adaptation to …

Liraglutide alleviated alpha-pyrrolidinovalerophenone (α-PVP) induced cognitive deficits in rats by modifying brain mitochondrial impairment

M Noruzi, H Behmadi, O Sabzevari… - European Journal of …, 2024 - Elsevier
The use of NPS compounds is increasing, and impairment in spatial learning and memory is
a growing concern. Alpha-pyrrolidinovalerophenone (α-PVP) consumption, as a commonly …

Conditioned overconsumption is dependent on reinforcer type in lean, but not obese, mice.

D Lewis-Sanders, S Bullich, MJ Olvera, J Vo… - Appetite, 2024 - Elsevier
Associative learning can drive many different types of behaviors, including food
consumption. Previous studies have shown that cues paired with food delivery while mice …