SIRT1 pathway in Parkinson's disease: a faraway snapshot but so close

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb… - …, 2023 - Springer
Silent information regulator (SIRT) has distinctive enzymatic activities and physiological
functions to control cell-cycle progression, gene expression, and DNA stability by targeting …

Role of reactive oxygen species in aging and age-related diseases: A review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

[HTML][HTML] Long noncoding RNA p21 enhances autophagy to alleviate endothelial progenitor cells damage and promote endothelial repair in hypertension through …

C Li, L Lin, L Zhang, R Xu, X Chen, J Ji, Y Li - Pharmacological Research, 2021 - Elsevier
Vascular damage of hypertension has been the focus of hypertension treatment, and
endothelial progenitor cells (EPCs) play an important role in the repair of vascular …

[HTML][HTML] Oxidative stress: a unifying paradigm in hypertension

RM Touyz, FJ Rios, R Alves-Lopes, KB Neves… - Canadian journal of …, 2020 - Elsevier
The etiology of hypertension involves complex interactions among genetic, environmental,
and pathophysiologic factors that influence many regulatory systems. Hypertension is …

[HTML][HTML] Cerebral consequences of environmental noise exposure

O Hahad, MTB Jimenez, M Kuntic, K Frenis… - Environment …, 2022 - Elsevier
The importance of noise exposure as a major environmental determinant of public health is
being increasingly recognized. While in recent years a large body evidence has emerged …

Effects of β-Blockers on the Sympathetic and Cytokines Storms in Covid-19

HM Al-Kuraishy, AI Al-Gareeb… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a causative virus in the
development of coronavirus disease 2019 (Covid-19) pandemic. Respiratory manifestations …

Exercise training and cardiac rehabilitation in COVID-19 patients with cardiovascular complications: state of art

M Calabrese, M Garofano, R Palumbo, P Di Pietro… - Life, 2021 - mdpi.com
Recent scientific literature has investigated the cardiovascular implications of COVID-19.
The mechanisms of cardiovascular damage seem to involve the protein angiotensin …

Effect of SGLT2 inhibitors on the sympathetic nervous system and blood pressure

AJ Scheen - Current cardiology reports, 2019 - Springer
Abstract Purpose of the Review Hyperactivity of sympathetic nervous system (SNS) plays a
role in the development of arterial hypertension and heart failure, two co-morbidities …

NADPH oxidase in the vasculature: Expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension

GA Knock - Free Radical Biology and Medicine, 2019 - Elsevier
The last 20–25 years have seen an explosion of interest in the role of NADPH oxidase
(NOX) in cardiovascular function and disease. In vascular smooth muscle and endothelium …

ACE2 (angiotensin-converting enzyme 2), COVID-19, and ACE inhibitor and Ang II (angiotensin II) receptor blocker use during the pandemic: the pediatric perspective

AM South, TM Brady, JT Flynn - Hypertension, 2020 - Am Heart Assoc
Potential but unconfirmed risk factors for coronavirus disease 2019 (COVID-19) in adults
and children may include hypertension, cardiovascular disease, and chronic kidney …