Antimicrobial resistance (AMR) in Clostridioides difficile remains a significant threat to global
healthcare systems, not just for the treatment of C. difficile infection (CDI), but as a reservoir …

ABSTRACT Introduction Updating data on Clostridioides difficile antibiotic resistance is
important for treatment improvement of C. difficile infections (CDIs). Areas covered Results …

Clostridium (Clostridioides) difficile infection (CDI) remains an urgent threat to patients in
health systems worldwide. Recurrent CDI occurs in up to 30% of cases due to sustained …

Clostridioides difficile is an obligate anaerobic pathogen among the most common causes of
healthcare-associated infections. It poses a global threat due to the clinical outcomes of …

Clostridioides difficile infection (CDI) is a common cause of nosocomial diarrhea. TcdB is a
major C. difficile exotoxin that activates macrophages to promote inflammation and epithelial …

Objectives The aim of this study was to provide an overview of the prevalence and molecular
characteristics of Clostridioides difficile infection (CDI) in China in the past 5 years. Methods …

Background Clostridioides difficile was listed as an urgent antimicrobial resistance (AMR)
threat in a report by the CDC in 2019. AMR drives the evolution of C. difficile and facilitates …

Abstract Background Clostridioides difficile (formerly Clostridium difficile) is well-
documented in Europe and North America to be a common cause of healthcare-associated …

We reviewed the molecular epidemiology of Clostridioides difficile infection (CDI) in Japan
by reviewing articles in which typing analysis was performed on recovered C. difficile …

Objectives The pharmacokinetics (PK)/pharmacodynamics (PD; PK/PD) characteristics of
fidaxomicin (FDX) and vancomycin (VCM) against Clostridioides difficile infection (CDI) are …