There are two basic sources of uncertainty in cancer chemotherapy: how much of the
therapeutic agent reaches the cancer cells, and how effective it is in reducing or controlling …

According to the prediction of the Global Cancer Observatory (GCO), an interactive web
platform that presents global cancer statistics, pancreatic ductal adenocarcinoma (PDAC) …

Cancer invasion and metastasis are major life-threatening events in patients with cancer, yet
the mechanisms by which cancer cells invade neighboring tissues remain poorly …

Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related
deaths in the US, despite only being the 11th most common cancer. Coupled with a 5-year …

Pancreatic cancer is one of the most lethal cancers and is currently the third leading cause
of cancer-related deaths in men and women (Society, 2017). The most common form of …

Despite the success of immunotherapy in many types of cancer, pancreatic adenocarcinoma
(PDAC) has yet to benefit. Innate immune cells are critical to antitumor immunosurveillance …

Pancreatic carcinoma poses a significant global health threat ranking as 6th leading cause
of cancer-related deaths. Distal pancreatic cancer, located in the body and tail of the …

Biliary tract carcinomas are rare, accounting for less than 1% of all cancers. However, their
incidence has recently increased in Japan and industrialized countries, such as the USA …

Abstract (EN) Background: Pancreatic ductal adenocarcinoma (PDAC), one of the fourth
most lethal malig-nancies in the world, has a less than 5% five-year relative overall survival …

Cancer is characterized by genetic mutations which interfere with the complex, well-
regulated signaling pathways governing cell behavior. When certain mutations accumulate …