The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
Smart nanoparticles for cancer therapy
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
Nanoparticles: Taking a unique position in medicine
TM Joseph, D Kar Mahapatra, A Esmaeili, Ł Piszczyk… - Nanomaterials, 2023 - mdpi.com
The human nature of curiosity, wonder, and ingenuity date back to the age of humankind. In
parallel with our history of civilization, interest in scientific approaches to unravel …
parallel with our history of civilization, interest in scientific approaches to unravel …
The evolution of commercial drug delivery technologies
AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …
products that improve patient health by enhancing the delivery of a therapeutic to its target …
Magnetic nanoparticles and clusters for magnetic hyperthermia: Optimizing their heat performance and developing combinatorial therapies to tackle cancer
H Gavilán, SK Avugadda… - Chemical Society …, 2021 - pubs.rsc.org
Magnetic hyperthermia (MHT) is a therapeutic modality for the treatment of solid tumors that
has now accumulated more than 30 years of experience. In the ongoing MHT clinical trials …
has now accumulated more than 30 years of experience. In the ongoing MHT clinical trials …
Strategies for delivering therapeutics across the blood–brain barrier
GC Terstappen, AH Meyer, RD Bell… - Nature Reviews Drug …, 2021 - nature.com
Achieving sufficient delivery across the blood–brain barrier is a key challenge in the
development of drugs to treat central nervous system (CNS) disorders. This is particularly …
development of drugs to treat central nervous system (CNS) disorders. This is particularly …
[HTML][HTML] Electrospinning for drug delivery applications: A review
Drug delivery devices are promising tools in the pharmaceutical field, as they are able to
maximize the therapeutic effects of the delivered drug while minimizing the undesired side …
maximize the therapeutic effects of the delivered drug while minimizing the undesired side …
[HTML][HTML] Periodontal disease: the good, the bad, and the unknown
LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …
Nanotechnology approaches for global infectious diseases
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of
malaria, tuberculosis and human immunodeficiency virus infection are particularly …
malaria, tuberculosis and human immunodeficiency virus infection are particularly …