The evolving story of incretins (GIP and GLP‐1) in metabolic and cardiovascular disease: a pathophysiological update
MA Nauck, DR Quast, J Wefers… - Diabetes, Obesity and …, 2021 - Wiley Online Library
The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …
The discovery and development of liraglutide and semaglutide
LB Knudsen, J Lau - Frontiers in endocrinology, 2019 - frontiersin.org
The discovery of glucagon-like peptide-1 (GLP-1), an incretin hormone with important effects
on glycemic control and body weight regulation, led to efforts to extend its half-life and make …
on glycemic control and body weight regulation, led to efforts to extend its half-life and make …
Glucagon-like peptide-1 receptor-based therapeutics for metabolic liver disease
JM Yabut, DJ Drucker - Endocrine Reviews, 2023 - academic.oup.com
Abstract Glucagon-like peptide-1 (GLP-1) controls islet hormone secretion, gut motility, and
body weight, supporting development of GLP-1 receptor agonists (GLP-1RA) for the …
body weight, supporting development of GLP-1 receptor agonists (GLP-1RA) for the …
Incretin hormones: Their role in health and disease
MA Nauck, JJ Meier - Diabetes, Obesity and Metabolism, 2018 - Wiley Online Library
Incretin hormones are gut peptides that are secreted after nutrient intake and stimulate
insulin secretion together with hyperglycaemia. GIP (glucose‐dependent insulinotropic …
insulin secretion together with hyperglycaemia. GIP (glucose‐dependent insulinotropic …
Glucagon-like peptide 1 in health and disease
In healthy individuals, the incretin hormone glucagon-like peptide 1 (GLP1) potentiates
insulin release and suppresses glucagon secretion in response to the ingestion of nutrients …
insulin release and suppresses glucagon secretion in response to the ingestion of nutrients …
Cardiovascular actions and clinical outcomes with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors
MA Nauck, JJ Meier, MA Cavender, M Abd El Aziz… - Circulation, 2017 - Am Heart Assoc
Potentiation of glucagon-like peptide-1 (GLP-1) action through selective GLP-1 receptor
(GLP-1R) agonism or by prevention of enzymatic degradation by inhibition of dipeptidyl …
(GLP-1R) agonism or by prevention of enzymatic degradation by inhibition of dipeptidyl …
[HTML][HTML] GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential
Type 2 diabetes mellitus (T2DM) is closely associated with cardiovascular diseases (CVD),
including atherosclerosis, hypertension and heart failure. Some anti-diabetic medications …
including atherosclerosis, hypertension and heart failure. Some anti-diabetic medications …
GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus
JJ Meier - Nature Reviews Endocrinology, 2012 - nature.com
In healthy humans, the incretin glucagon-like peptide 1 (GLP-1) is secreted after eating and
lowers glucose concentrations by augmenting insulin secretion and suppressing glucagon …
lowers glucose concentrations by augmenting insulin secretion and suppressing glucagon …
Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, glycemic parameters, appetite and energy metabolism in obese, non-diabetic adults
J Van Can, B Sloth, CB Jensen, A Flint… - International journal of …, 2014 - nature.com
Objective: We investigated the effects of liraglutide on gastric emptying, glycemic
parameters, appetite and energy metabolism in obese non-diabetic individuals. Design …
parameters, appetite and energy metabolism in obese non-diabetic individuals. Design …
Xylooligosaccharides as prebiotics from agricultural by-products: Production and applications
AK Samanta, N Jayapal, C Jayaram, S Roy… - … and Dietary Fibre, 2015 - Elsevier
The growing demands of novel food products for well-being and age related issues coupled
with increasing health care expenditure has attracted global attention on prebiotics. During …
with increasing health care expenditure has attracted global attention on prebiotics. During …