Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation,
mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced …

ABSTRACT Introduction Sesquiterpene lactones (SLs) are one of the most diverse bioactive
secondary metabolites found in plants and exhibit a broad range of therapeutic properties …

Abstract Background Atractylenolide I (AI) is a natural sesquiterpene lactone isolated from
Atractylodes macrocephala Koidz, known as Baizhu in traditional Chinese medicine. AI has …

Simple Summary The primary characteristics of cancer cachexia are weakness, weight loss,
atrophy, fat reduction, and systemic inflammation. Cachexia is strongly associated with …

Cancer cachexia is a complex systemic catabolism syndrome characterized by muscle
wasting. It affects multiple distant organs and their crosstalk with cancer constitute cancer …

Wasting in cancer patients has long been recognized as a condition that adversely affects
cancer patients' quality of life, treatment tolerance, and oncological outcomes. Historically …

Inflammatory coagulopathy is resulted from endothelial dysfunction and platelet
hyperactivation in inflammatory diseases. In this study, the effects of baicalin, an active …

Cancer‐derived exosomes are involved in the development of cancer cachexia. Carnosol,
which exhibited ameliorating effects on cancer cachexia of C26 tumour‐bearing mice in our …

Cancer-associated cachexia (CAC) is the nutrition-independent loss of lean muscle and
adipose tissues, and results in reduced chemotherapy effectiveness and increased mortality …

Introduction: Carnosol exhibited ameliorating effects on muscle atrophy of mice developed
cancer cachexia in our previous research. Method: Here, the ameliorating effects of carnosol …