Lysine crotonylation: an emerging player in DNA damage response
The DNA damage response (DDR) system plays an important role in maintaining genome
stability and preventing related diseases. The DDR network comprises many proteins and …
stability and preventing related diseases. The DDR network comprises many proteins and …
Protein O-GlcNAcylation regulates DNA damage response: A novel target for cancer therapy
Z Zhu, S Li, X Yin, K Sun, J Song, W Ren, L Gao… - International Journal of …, 2024 - Elsevier
The DNA damage response (DDR) safeguards the stable genetic information inheritance by
orchestrating a complex protein network in response to DNA damage. However, this …
orchestrating a complex protein network in response to DNA damage. However, this …
The Role of Mechanotransduction in Contact Inhibition of Locomotion and Proliferation
F Nakamura - International Journal of Molecular Sciences, 2024 - mdpi.com
Contact inhibition (CI) represents a crucial tumor-suppressive mechanism responsible for
controlling the unbridled growth of cells, thus preventing the formation of cancerous tissues …
controlling the unbridled growth of cells, thus preventing the formation of cancerous tissues …
Recruitment Kinetics of XRCC1 and RNF8 Following MeV Proton and α-Particle Micro-Irradiation
G Muggiolu, E Torfeh, M Simon, G Devès, H Seznec… - Biology, 2023 - mdpi.com
Simple Summary We used the charged-particle microbeam installed at the AIFIRA facility to
perform micro-irradiation experiments and measure the recruitment kinetics of DNA …
perform micro-irradiation experiments and measure the recruitment kinetics of DNA …
H2B oncohistones cause homologous recombination defect and genomic instability through reducing H2B monoubiquitination in Schizosaccharomyces pombe
B Qin, G Lu, X Chen, C Zheng, H Lin, Q Liu… - Journal of Biological …, 2024 - ASBMB
Canonical oncohistones are histone H3 mutations in the N-terminal tail associated with
tumors and affect gene expression by altering H3 post-translational modifications (PTMs) …
tumors and affect gene expression by altering H3 post-translational modifications (PTMs) …
Contact Inhibition and Mechanotransduction
F Nakamura - 2023 - preprints.org
Contact inhibition (CI) represents a crucial tumor-suppressive mechanism responsible for
controlling the unbridled growth of cells, thus preventing the formation of cancerous tissues …
controlling the unbridled growth of cells, thus preventing the formation of cancerous tissues …
[图书][B] Biophysical and Structural Analyses of HECT E3 Ubiquitin Ligase HERC2 RLD Domains and Their Implications in Neurodevelopmental Disorders and DNA …
M Oka - 2023 - search.proquest.com
Homologous to the E6AP carboxyl terminus (HECT) and regulator of chromosome
condensation 1 (RCC1)-like domain-containing protein 2 (HERC2) is one of the large HECT …
condensation 1 (RCC1)-like domain-containing protein 2 (HERC2) is one of the large HECT …
[引用][C] Recruitment Kinetics of XRCC1 and RNF8 Following MeV Proton and α-Particle Micro-Irradiation. Biology 2023, 12, 921
G Muggiolu, E Torfeh, M Simon, G Devès, H Seznec… - 2023 - europepmc.org
Time-lapse fluorescence imaging coupled to micro-irradiation devices provides information
on the kinetics of DNA repair protein accumulation, from a few seconds to several minutes …
on the kinetics of DNA repair protein accumulation, from a few seconds to several minutes …