Cellular and Molecular Roles of Immune Cells in the Gut-Brain Axis in Migraine
Y Zhou, M Pang, Y Ma, L Lu, J Zhang, P Wang… - Molecular …, 2024 - Springer
Migraine is a complex and multi-system dysfunction. The realization of its pathophysiology
and diagnosis is developing rapidly. Migraine has been linked to gastrointestinal disorders …
and diagnosis is developing rapidly. Migraine has been linked to gastrointestinal disorders …
“Headache and epilepsy”—how are they connected?
The relationship between headache and seizures is a complicated one, since these two
conditions are related in numerous ways. Although the nature of this association is unclear …
conditions are related in numerous ways. Although the nature of this association is unclear …
[HTML][HTML] Role of peptidergic nerve terminals in the skin: reversal of thermal sensation by calcitonin gene-related peptide in TRPV1-depleted neuropathy
To investigate the contribution of peptidergic intraepidermal nerve fibers (IENFs) to
nociceptive responses after depletion of the thermal-sensitive receptor, transient receptor …
nociceptive responses after depletion of the thermal-sensitive receptor, transient receptor …
[HTML][HTML] New insights on metabolic and genetic basis of migraine: novel impact on management and therapeutical approach
I Simonetta, R Riolo, F Todaro… - International Journal of …, 2022 - mdpi.com
Migraine is a hereditary disease, usually one-sided, sometimes bilateral. It is characterized
by moderate to severe pain, which worsens with physical activity and may be associated …
by moderate to severe pain, which worsens with physical activity and may be associated …
Anti-CGRP compositions and use thereof
BR Kovacevich, LF Garcia-Martinez, K Olson… - US Patent …, 2017 - Google Patents
2012-08-01 Assigned to ALDERBIO HOLDINGS LLC reassignment ALDERBIO HOLDINGS
LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …
LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …
Patient selection for migraine preventive treatment with anti-CGRP (r) monoclonal antibodies
A Negro, P Martelletti - Expert Review of Neurotherapeutics, 2019 - Taylor & Francis
Introduction: Migraine is the most common neurological disorder and represents the first
cause of disability in under 50s in both genders. Available preventive drugs were primarily …
cause of disability in under 50s in both genders. Available preventive drugs were primarily …
CGRP-based migraine therapeutics: how might they work, why so safe, and what next?
AF Russo - ACS pharmacology & translational science, 2018 - ACS Publications
Migraine is a debilitating neurological condition that involves the neuropeptide calcitonin
gene-related peptide (CGRP). An exciting development is the recent FDA approval of the …
gene-related peptide (CGRP). An exciting development is the recent FDA approval of the …
The effects of tempol on cyclophosphamide‐induced oxidative stress in rat micturition reflexes
EJ Gonzalez, A Peterson, S Malley… - The Scientific World …, 2015 - Wiley Online Library
We hypothesized that cyclophosphamide‐(CYP‐) induced cystitis results in oxidative stress
and contributes to urinary bladder dysfunction. We determined (1) the expression of …
and contributes to urinary bladder dysfunction. We determined (1) the expression of …
Mast cell activation disease and the modern epidemic of chronic inflammatory disease
LB Afrin - Translational Research, 2016 - Elsevier
A large and growing portion of the human population, especially in developed countries,
suffers 1 or more chronic, often quite burdensome ailments which either are overtly …
suffers 1 or more chronic, often quite burdensome ailments which either are overtly …
Erenumab in the treatment of migraine
Migraine is a highly prevalent neurological pain syndrome, and its management is limited
due to side effects posed by current preventive therapies. Calcitonin gene-related peptide …
due to side effects posed by current preventive therapies. Calcitonin gene-related peptide …