Introduction: Trisomy 8 is one of the most common cytogenetic alterations in acute myeloid
leukemia (AML), with a frequency between 10% and 15%. Areas covered: The authors …

Simple Summary The low incidence (1: 1,000,000) of chronic myeloid leukemia (CML) in the
first two decades of life presents an obstacle to accumulation of pediatric experience and …

Myeloid sarcoma (MS) is a neoplastic condition composed of immature myeloid cells
involving an extramedullary site. We investigated underlying chromosomal and molecular …

Summary Interferon regulatory factor 8 (IRF8) is a member of the IRF family that is specific to
the hematopoietic cell and is involved in regulating the development of human monocytic …

Myeloid sarcoma (MS) as a solid extra-medullary (EM) manifestation of acute myeloid
leukemia (AML), myeloproliferative or myelodysplastic syndromes is a rare presentation of …

Purpose The impact of myeloid sarcoma (MS) on clinical outcome of pediatric acute myeloid
leukemia (AML) patients remains controversial. Moreover, little is known about the role of …

Isolated myeloid sarcoma (MS) is a rare malignancy in which myeloid blast forms tumors at
various locations while the bone marrow (BM) remains cytomorphologically free from …

The molecular mechanism of myeloid sarcoma (MS) formation remains nuclear. Our clinical
and mouse model findings from a previous study revealed that cooperation of KMT2A (MLL) …

Chronic myeloid leukemia (CML) is a slow-growing type of cancer that originates in the
blood-forming cells of the bone marrow and is caused by a chromosomal mutation that is …

Objective To investigate the characteristics of hematological malignancies in patients with
the SET-CAN fusion gene and provide a literature review. Methods We retrospectively …