Organelles compartmentalize eukaryotic cells, enhancing their ability to respond to
environmental and developmental changes. One way in which organelles communicate and …

Myelin is critical for the proper function of the nervous system and one of the most complex
cell–cell interactions of the body. Myelination allows for the rapid conduction of action …

Mitochondria-lysosome contacts are recently identified sites for mediating crosstalk between
both organelles, but their role in normal and diseased human neurons remains unknown. In …

Interfaces between organelles are emerging as critical platforms for many biological
responses in eukaryotic cells. In yeast, the ERMES complex is an endoplasmic reticulum …

Cellular Ca 2+ homeostasis is maintained through the integrated and coordinated function
of Ca 2+ transport molecules, Ca 2+ buffers and sensors. These molecules are associated …

Membrane contact sites enable interorganelle communication by positioning organelles in
close proximity using molecular" tethers." With a growing understanding of the importance of …

Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis with
associated frontotemporal dementia (ALS/FTD) are major neurodegenerative diseases for …

Abstract α-Synuclein is strongly linked to Parkinson's disease but the molecular targets for its
toxicity are not fully clear. However, many neuronal functions damaged in Parkinson's …

The role of cuticle changes in insecticide resistance in the major malaria vector Anopheles
gambiae was assessed. The rate of internalization of 14C deltamethrin was significantly …

Several proteins at endoplasmic reticulum (ER)-Golgi membrane contact sites contain a PH
domain that interacts with the Golgi phosphoinositide PI (4) P, a FFAT motif that interacts …