Recent advances in the genetics of idiopathic pulmonary fibrosis

P Spagnolo, JS Lee - Current Opinion in Pulmonary Medicine, 2023 - journals.lww.com
Recent advances in the genetics of idiopathic pulmonary fibr... : Current Opinion in Pulmonary
Medicine Recent advances in the genetics of idiopathic pulmonary fibrosis : Current Opinion …

Cancer treatments as paradoxical catalysts of tumor awakening in the lung

E Nicolas, B Kosmider, E Cukierman… - Cancer and Metastasis …, 2024 - Springer
Much of the fatality of tumors is linked to the growth of metastases, which can emerge
months to years after apparently successful treatment of primary tumors. Metastases arise …

Genetics and genomics of pulmonary fibrosis: charting the molecular landscape and shaping precision medicine

A Adegunsoye, JA Kropski, J Behr… - American Journal of …, 2024 - atsjournals.org
Recent genetic and genomic advancements have elucidated the complex etiology of
idiopathic pulmonary fibrosis (IPF) and other progressive fibrotic interstitial lung diseases …

Clinical, radiological and histopathological features of patients with familial pulmonary fibrosis

H Jaula, L Mattila, E Lappi-Blanco, J Salonen… - Respiratory …, 2024 - Springer
Background In familial pulmonary fibrosis (FPF) at least two biological relatives are affected.
Patients with FPF have diverse clinical features. Research question We aimed to …

High risk of lung cancer in surfactant-related gene variant carriers

A Brudon, M Legendre, A Mageau… - European …, 2024 - Eur Respiratory Soc
Background Several rare surfactant-related gene (SRG) variants associated with interstitial
lung disease are suspected to be associated with lung cancer, but data are missing. We …

Phage Immunoprecipitation‐Sequencing Reveals CDHR5 Autoantibodies in Select Patients With Interstitial Lung Disease

V Upadhyay, Y Yoon, SE Vazquez… - ACR Open …, 2024 - Wiley Online Library
Objective Interstitial lung diseases (ILDs) are a heterogeneous group of disorders that can
develop in patients with connective tissue diseases. Establishing autoimmunity in ILD …

MMP19 Variants in Familial and Sporadic Idiopathic Pulmonary Fibrosis

Y Fan, C Zheng, R Ma, J Wang, S Yang, Q Ye - Lung, 2023 - Springer
Background Gene variants have been identified in patients with familial or sporadic
idiopathic pulmonary fibrosis (IPF). These variants may partially account for the genetic risk …

Genetic factors for ILD—the path of precision medicine

G Raghu, JM Torres, RL Bennett - The Lancet Respiratory Medicine, 2024 - thelancet.com
With increasing awareness of genetic factors and variants involved in the pathogenesis of
interstitial lung diseases (ILDs) and expanded availability of genetic testing, pulmonologists …

[HTML][HTML] Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis

A Vannan, R Lyu, AL Williams, NM Negretti, ED Mee… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The human lung is structurally complex, with a diversity of specialized epithelial, stromal and
immune cells playing specific functional roles in anatomically distinct locations, and large …

PhIP-Seq uncovers novel autoantibodies and unique endotypes in interstitial lung disease

V Upadhyay, Y Yoon, SE Vazquez, TE Velez, KD Jones… - bioRxiv, 2023 - biorxiv.org
Interstitial lung diseases (ILDs) are a heterogeneous group of disorders that can develop in
patients with connective tissue diseases (CTD). Establishing autoimmunity in ILD impacts …