Evaluation of the anti-diabetic activity of some common herbs and spices: providing new insights with inverse virtual screening

ASP Pereira, AJ Banegas-Luna, J Peña-García… - Molecules, 2019 - mdpi.com
Culinary herbs and spices are widely used as a traditional medicine in the treatment of
diabetes and its complications, and there are several scientific studies in the literature …

Protective and therapeutic effects of natural products against diabetes mellitus via regenerating pancreatic β‐cells and restoring their dysfunction

DK Semwal, A Kumar, S Aswal… - Phytotherapy …, 2021 - Wiley Online Library
Diabetes mellitus is a growing public health concern and an increasing interest has been
raised to search for new compounds with therapeutic effects on β‐cells. There are chronic …

Protective effects of Cynara scolymus leaves extract on metabolic disorders and oxidative stress in alloxan-diabetic rats

M Ben Salem, R Ben Abdallah Kolsi, R Dhouibi… - … and alternative medicine, 2017 - Springer
Background Diabetes mellitus (DM) is associated with hyperglycemia, inflammatory
disorders and abnormal lipid profiles, currently the extracts from leaves of cynara scolymus …

Antidiabetic effect of Achillea millefollium through multitarget interactions: α-glucosidases inhibition, insulin sensitization and insulin secretagogue activities

F Chávez-Silva, L Cerón-Romero, L Arias-Durán… - Journal of …, 2018 - Elsevier
Ethnopharmacological importance Achillea millefolium L.(Asteraceae) is a perennial herb
used in Mexican folk medicine for treatment of several pathologies, including inflammatory …

Mechanism of action of anti-hypercholesterolemia drugs and their resistance

V Tiwari, M Khokhar - European Journal of Pharmacology, 2014 - Elsevier
Coronary artery disease is one of the leading causes of death worldwide. One of the
significant causes of this disease is hypercholesterolemia which is the result of various …

Bee Pollen Polysaccharide From Rosa rugosa Thunb. (Rosaceae) Promotes Pancreatic β-Cell Proliferation and Insulin Secretion

S Yang, Y Qu, J Chen, S Chen, L Sun… - Frontiers in …, 2021 - frontiersin.org
Insufficient pancreatic β-cell or insulin-producing β-cell are implicated in all types of diabetes
mellitus. Our previous studies showed bee pollen polysaccharide RBPP-P improves insulin …

Hydroalcoholic extract of Achillea millefolium improved blood glucose, liver enzymes and lipid profile compared to metformin in streptozotocin-induced diabetic rats

S Rezaei, F Ashkar, F Koohpeyma… - Lipids in health and …, 2020 - Springer
Background Recent studies have reported that herbal extracts may have some protective
effect against the complications of diabetes mellitus. This study aimed to investigate the …

Phytochemical composition, protective and therapeutic effect on gastric ulcer and α-amylase inhibitory activity of Achillea biebersteinii Afan.

HI Abd-Alla, NMM Shalaby, MA Hamed… - Archives of pharmacal …, 2016 - Springer
Three sesquiterpene lactones [two germacranolides (micranthin and sintenin) and one
guaianolide (4β, 10α-dihydroxy-5β, 7β, 8βH-guaia-1, 11 (13) dien-12, 8α-olide)] and four …

Germacranolide-and guaianolide-type sesquiterpenoids from Achillea alpina L. reduce insulin resistance in palmitic acid-treated HepG2 cells via inhibition of the …

GM Xue, CG Zhao, JF Xue, K Du, JJ Duan, H Pan, M Li… - Phytochemistry, 2022 - Elsevier
Chemical investigation on the aerial part of Achillea alpina L. led to the isolation of twenty
sesquiterpenoids. The structures of the undescribed achigermalides A–H were determined …

Effect of Artichoke (cynara scolymus) on cardiac markers, lipid profile and antioxidants levels in tissue of HFD-induced obesity

M Ben Salem, H Affes, R Dhouibi, S Charfi… - … of physiology and …, 2022 - Taylor & Francis
Obesity plays a pivotal role in the insulin resistance disease, which is related to
hypertension, hyperlipidemia, type 2 diabetes mellitus, and an increased risk of …