LncRNA-miRNA interaction is involved in colorectal cancer pathogenesis by modulating diverse signaling pathways

SH Alshahrani, ZSM Al-Hadeithi, SG Almalki… - … -Research and Practice, 2023 - Elsevier
LncRNAs function as molecular sponges for miRNAs to control their availability for targeting
mRNA molecules. This procedure indirectly regulates the expression of cancer-related …

[HTML][HTML] MicroRNAs as critical biomarkers of major depressive disorder: a comprehensive perspective

MA Ortega, MA Alvarez-Mon, C García-Montero… - Biomedicines, 2021 - mdpi.com
Major Depressive Disorder (MDD) represents a major global health concern, a body-mind
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …

Discerning the prospects of miRNAs as a multi-target therapeutic and diagnostic for alzheimer's disease

D Bhatnagar, S Ladhe, D Kumar - Molecular Neurobiology, 2023 - Springer
Although over the last few decades, numerous attempts have been made to halt Alzheimer's
disease (AD) progression and mitigate its symptoms, only a few have been proven …

[HTML][HTML] miR-205: a potential biomedicine for cancer therapy

N Chauhan, A Dhasmana, M Jaggi, SC Chauhan… - Cells, 2020 - mdpi.com
microRNAs (miRNAs) are a class of small non-coding RNAs that regulate the expression of
their target mRNAs post transcriptionally. miRNAs are known to regulate not just a gene but …

Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; an updated review

S Zanganeh, N Goodarzi, M Doroudian… - Reviews in Medical …, 2022 - Wiley Online Library
COVID‐19 has spread swiftly throughout the world posing a global health emergency. The
significant numbers of deaths attributed to this pandemic have researchers battling to …

Progress in the molecular pathogenesis and nucleic acid therapeutics for Parkinson's disease in the precision medicine era

D Li, FL Mastaglia, S Fletcher… - Medicinal Research …, 2020 - Wiley Online Library
Parkinson's disease (PD) is one of the most common neurodegenerative disorders that
manifest various motor and nonmotor symptoms. Although currently available therapies can …

Control of selective mRNA translation in neuronal subcellular compartments in health and disease

R Cagnetta, JG Flanagan… - Journal of …, 2023 - Soc Neuroscience
In multiple cell types, mRNAs are transported to subcellular compartments, where local
translation enables rapid, spatially localized, and specific responses to external stimuli …

Role of microRNAs in the pathophysiology of addiction

AM Gowen, KE Odegaard, J Hernandez… - Wiley …, 2021 - Wiley Online Library
Addiction is a chronic and relapsing brain disorder characterized by compulsive seeking
despite adverse consequences. There are both heritable and epigenetic mechanisms …

[HTML][HTML] Lipoplexes for effective in vitro delivery of microRNAs to adult human cardiac fibroblasts for perspective direct cardiac cell reprogramming

L Nicoletti, C Paoletti, G Tarricone, I Andreana… - … , Biology and Medicine, 2022 - Elsevier
Abstract Design of nanocarriers for efficient miRNA delivery can significantly improve miRNA-
based therapies. Lipoplexes based on helper lipid, dioleoyl phosphatidylethanolamine …

[HTML][HTML] The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases

E Oveili, S Vafaei, H Bazavar, Y Eslami… - Cell Communication and …, 2023 - Springer
MicroRNAs (miRNAs) are a group of small non-coding RNAs that regulate gene expression
by targeting mRNA. Moreover, it has been shown that miRNAs expression are changed in …