LncRNA-miRNA interaction is involved in colorectal cancer pathogenesis by modulating diverse signaling pathways
LncRNAs function as molecular sponges for miRNAs to control their availability for targeting
mRNA molecules. This procedure indirectly regulates the expression of cancer-related …
mRNA molecules. This procedure indirectly regulates the expression of cancer-related …
[HTML][HTML] MicroRNAs as critical biomarkers of major depressive disorder: a comprehensive perspective
MA Ortega, MA Alvarez-Mon, C García-Montero… - Biomedicines, 2021 - mdpi.com
Major Depressive Disorder (MDD) represents a major global health concern, a body-mind
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …
Discerning the prospects of miRNAs as a multi-target therapeutic and diagnostic for alzheimer's disease
D Bhatnagar, S Ladhe, D Kumar - Molecular Neurobiology, 2023 - Springer
Although over the last few decades, numerous attempts have been made to halt Alzheimer's
disease (AD) progression and mitigate its symptoms, only a few have been proven …
disease (AD) progression and mitigate its symptoms, only a few have been proven …
[HTML][HTML] miR-205: a potential biomedicine for cancer therapy
N Chauhan, A Dhasmana, M Jaggi, SC Chauhan… - Cells, 2020 - mdpi.com
microRNAs (miRNAs) are a class of small non-coding RNAs that regulate the expression of
their target mRNAs post transcriptionally. miRNAs are known to regulate not just a gene but …
their target mRNAs post transcriptionally. miRNAs are known to regulate not just a gene but …
Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; an updated review
COVID‐19 has spread swiftly throughout the world posing a global health emergency. The
significant numbers of deaths attributed to this pandemic have researchers battling to …
significant numbers of deaths attributed to this pandemic have researchers battling to …
Progress in the molecular pathogenesis and nucleic acid therapeutics for Parkinson's disease in the precision medicine era
Parkinson's disease (PD) is one of the most common neurodegenerative disorders that
manifest various motor and nonmotor symptoms. Although currently available therapies can …
manifest various motor and nonmotor symptoms. Although currently available therapies can …
Control of selective mRNA translation in neuronal subcellular compartments in health and disease
R Cagnetta, JG Flanagan… - Journal of …, 2023 - Soc Neuroscience
In multiple cell types, mRNAs are transported to subcellular compartments, where local
translation enables rapid, spatially localized, and specific responses to external stimuli …
translation enables rapid, spatially localized, and specific responses to external stimuli …
Role of microRNAs in the pathophysiology of addiction
AM Gowen, KE Odegaard, J Hernandez… - Wiley …, 2021 - Wiley Online Library
Addiction is a chronic and relapsing brain disorder characterized by compulsive seeking
despite adverse consequences. There are both heritable and epigenetic mechanisms …
despite adverse consequences. There are both heritable and epigenetic mechanisms …
[HTML][HTML] Lipoplexes for effective in vitro delivery of microRNAs to adult human cardiac fibroblasts for perspective direct cardiac cell reprogramming
Abstract Design of nanocarriers for efficient miRNA delivery can significantly improve miRNA-
based therapies. Lipoplexes based on helper lipid, dioleoyl phosphatidylethanolamine …
based therapies. Lipoplexes based on helper lipid, dioleoyl phosphatidylethanolamine …
[HTML][HTML] The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases
E Oveili, S Vafaei, H Bazavar, Y Eslami… - Cell Communication and …, 2023 - Springer
MicroRNAs (miRNAs) are a group of small non-coding RNAs that regulate gene expression
by targeting mRNA. Moreover, it has been shown that miRNAs expression are changed in …
by targeting mRNA. Moreover, it has been shown that miRNAs expression are changed in …