The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases
E Oveili, S Vafaei, H Bazavar, Y Eslami… - Cell Communication and …, 2023 - Springer
MicroRNAs (miRNAs) are a group of small non-coding RNAs that regulate gene expression
by targeting mRNA. Moreover, it has been shown that miRNAs expression are changed in …
by targeting mRNA. Moreover, it has been shown that miRNAs expression are changed in …
Regulation and therapeutic potentials of microRNAs to non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for
80%–85% of total cases and leading to millions of deaths worldwide. Drug resistance is the …
80%–85% of total cases and leading to millions of deaths worldwide. Drug resistance is the …
[HTML][HTML] Lipoplexes for effective in vitro delivery of microRNAs to adult human cardiac fibroblasts for perspective direct cardiac cell reprogramming
Abstract Design of nanocarriers for efficient miRNA delivery can significantly improve miRNA-
based therapies. Lipoplexes based on helper lipid, dioleoyl phosphatidylethanolamine …
based therapies. Lipoplexes based on helper lipid, dioleoyl phosphatidylethanolamine …
miRNA molecules—late breaking treatment for inflammatory bowel diseases?
I Aggeletopoulou, A Mouzaki, K Thomopoulos… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs) are a group of non-coding RNAs that play a critical role in regulating
epigenetic mechanisms in inflammation-related diseases. Inflammatory bowel diseases …
epigenetic mechanisms in inflammation-related diseases. Inflammatory bowel diseases …
Engineering multifunctional adhesive hydrogel patches for biomedical applications
Traditional patches, such as sticking plaster or acrylic adhesives used for over a hundred
years, lack functionality. To address this issue of poor functionality, adhesive hydrogel …
years, lack functionality. To address this issue of poor functionality, adhesive hydrogel …
Targeting and delivery of microRNA-targeting antisense oligonucleotides in cardiovascular diseases
G Saenz-Pipaon, DA Dichek - Atherosclerosis, 2023 - Elsevier
Discovered three decades ago, microRNAs (miRNAs) are now recognized as key players in
the pathophysiology of multiple human diseases, including those affecting the …
the pathophysiology of multiple human diseases, including those affecting the …
[HTML][HTML] Molecular camouflage by a context-specific hydrogel as the key to unlock the potential of viral vector gene therapy
Gene therapy offers hope for currently untreatable diseases; the patient's own cellular
machinery is recruited to create therapeutics. However, unpredictable responses that lead to …
machinery is recruited to create therapeutics. However, unpredictable responses that lead to …
[HTML][HTML] Stage-specific treatment of colorectal cancer: A microRNA-nanocomposite approach
Colorectal cancer (CRC) is among the leading causes of cancer mortality. The lifetime risk of
developing CRC is about 5% in adult males and females. CRC is usually diagnosed at an …
developing CRC is about 5% in adult males and females. CRC is usually diagnosed at an …
Treating Alzheimer's disease using nanoparticle-mediated drug delivery strategies/systems
AK Roghani, RI Garcia, A Roghani, A Reddy… - Ageing Research …, 2024 - Elsevier
The administration of promising medications for the treatment of neurodegenerative
disorders (NDDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's …
disorders (NDDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's …
Interactions among long non-coding RNAs and microRNAs influence disease phenotype in diabetes and diabetic kidney disease
SP Srivastava, JE Goodwin, P Tripathi… - International Journal of …, 2021 - mdpi.com
Large-scale RNA sequencing and genome-wide profiling data revealed the identification of
a heterogeneous group of noncoding RNAs, known as long noncoding RNAs (lncRNAs) …
a heterogeneous group of noncoding RNAs, known as long noncoding RNAs (lncRNAs) …