microRNA expression in acute myeloid leukaemia: New targets for therapy?
D Fletcher, E Brown, J Javadala, P Uysal‐Onganer… - …, 2022 - Wiley Online Library
Recent studies have shown that short non‐coding RNAs, known as microRNAs (miRNAs)
and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia …
and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia …
Clinical Insights into MicroRNAs in Depression: Bridging Molecular Discoveries and Therapeutic Potential
L Kaurani - International Journal of Molecular Sciences, 2024 - mdpi.com
Depression is a major contributor to the overall global burden of disease. The discovery of
biomarkers for diagnosis or prediction of treatment responses and as therapeutic agents is a …
biomarkers for diagnosis or prediction of treatment responses and as therapeutic agents is a …
In vitro naive CD4+ T cell differentiation upon treatment with miR-29b-loaded exosomes from mesenchymal stem cells
Background Gene regulation by microRNA (miRNA) is central in T lymphocytes
differentiation processes. Here, we investigate miRNA-29b (miR-29b) roles in the …
differentiation processes. Here, we investigate miRNA-29b (miR-29b) roles in the …
Small non-coding RNAs in soft-tissue sarcomas: State of the art and future directions
Soft-tissue sarcomas (STS) are a rare and heterogeneous group of tumors that arise from
connective tissue and can occur anywhere in the body. Among the plethora of over 50 …
connective tissue and can occur anywhere in the body. Among the plethora of over 50 …
An adenoviral vector as a versatile tool for delivery and expression of miRNAs
J Scholz, PP Weil, D Pembaur, G Koukou, M Aydin… - Viruses, 2022 - mdpi.com
Only two decades after discovering miRNAs, our understanding of the functional effects of
deregulated miRNAs in the development of diseases, particularly cancer, has been rapidly …
deregulated miRNAs in the development of diseases, particularly cancer, has been rapidly …
Small non-coding RNAs: do they encode answers for controlling SARS-CoV-2 in the future?
P Bhattacharyya, SC Biswas - Frontiers in Microbiology, 2020 - frontiersin.org
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel coronavirus
responsible for the current COVID-19 (coronavirus disease 2019) pandemic, which has hit …
responsible for the current COVID-19 (coronavirus disease 2019) pandemic, which has hit …
The regulation of CD47-SIRPα signaling axis by microRNAs in combination with conventional cytotoxic drugs together with the help of nano-delivery: a choice for …
Z Beizavi, SM Gheibihayat, H Moghadasian… - Molecular Biology …, 2021 - Springer
CD47, a member of the immunoglobulin superfamily, is an important “Don't Eat-Me” signal in
phagocytosis process [clearance of apoptotic cells] as well as a regulator of the adaptive …
phagocytosis process [clearance of apoptotic cells] as well as a regulator of the adaptive …
Liposome-Mediated Anti-Viral Drug Delivery Across Blood–Brain Barrier: Can Lipid Droplet Target Be Game Changers?
S Mondal, S Ghosh - Cellular and Molecular Neurobiology, 2024 - Springer
Lipid droplets (LDs) are subcellular organelles secreted from the endoplasmic reticulum
(ER) that play a major role in lipid homeostasis. Recent research elucidates additional roles …
(ER) that play a major role in lipid homeostasis. Recent research elucidates additional roles …
Approaches based on miRNAs in Behçet's Disease: Unveiling pathogenic mechanisms, diagnostic strategies, and therapeutic applications
Behçet's Disease (BD) is an intricate medical puzzle, captivating researchers with its
enigmatic pathogenesis. This complex ailment, distinguished by recurrent mouth and genital …
enigmatic pathogenesis. This complex ailment, distinguished by recurrent mouth and genital …
[HTML][HTML] Insight into the role of non-coding RNA in the diagnosis and treatment of retinitis pigmentosa
J Chen, W Liu, S Niu, Y Zheng, S Lin, Y Hong - Non-coding RNA Research, 2024 - Elsevier
Retinitis pigmentosa (RP) is the most common type of inherited retinal dystrophy. The course
of RP is irreversible and leads to progressive loss of vision. It is characterized by hypotrophic …
of RP is irreversible and leads to progressive loss of vision. It is characterized by hypotrophic …