Anthocyanins are natural products that give color to plants. As natural plant pigments,
anthocyanins also have a series of health-promoting benefits. Many researchers have …

The nucleotide-binding domain leucine-rich repeat-receptor, pyrin domain-containing-3
(NLRP3) inflammasome contributes to the inflammatory response by activating caspase-1 …

Mounting evidence has suggested that modulating microglia polarization from pro-
inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic …

Maize is one of the most important crops for human and animal consumption and contains a
chemical arsenal essential for survival: flavonoids. Moreover, flavonoids are well known for …

Alcoholic liver disease (ALD) is caused by chronic excessive alcohol consumption, which
leads to inflammation, oxidative stress, lipid accumulation, liver fibrosis/cirrhosis, and even …

The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome pathway is
mainly responsible for the activation and release of a cascade of proinflammatory mediators …

Inflammasomes, particularly the nucleotide-binding oligomerization domain, leucine-rich
repeat, and pyrin domain containing 3 (NLRP3) inflammasome, apparently serve as crucial …

Acetaminophen (APAP) overdose-induced hepatotoxicity is the most common cause of drug-
induced liver injury worldwide, which is significantly linked to oxidative stress and sterile …

Objectives Despite the recent attention focused on the roles of the NLRP3 inflammasome in
the pathogenesis of metabolic and inflammatory diseases, little is known about the activation …

Inflammasomes are key intracellular multimeric proteins able to initiate the cellular
inflammatory signaling pathway. NLRP3 inflammasome represents one of the main protein …