Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …

While the links between metabolic dysfunction associated steatotic liver disease liver
disease (MASLD) and obesity, insulin resistance are widely appreciated, there are a host of …

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease associated with the
pathological accumulation of lipids inside hepatocytes. Untreated NAFL can progress to non …

Nonalcoholic fatty liver disease (NAFLD) affects approximately 25% of the adult population
worldwide. This pathology can progress into end-stage liver disease with life-threatening …

Non‐alcoholic fatty liver disease (NAFLD) is a disorder characterized by excessive
accumulation of fat in the liver that can progress to liver inflammation (non‐alcoholic …

Regular exercise has both immediate and long-lasting benefits on cardiometabolic health,
and has been recommended as a cornerstone of treatment in the management of diabetes …

Lanifibranor, a pan-PPAR agonist, improves liver histology in patients with metabolic
dysfunction-associated steatohepatitis (MASH), who have poor cardiometabolic health …

Role of steatotic liver disease in prediction and prevention of cardiometabolic diseases |
Nature Reviews Gastroenterology & Hepatology Skip to main content Thank you for visiting …

Background Adiposity has been previously associated with cognitive impairment and
Alzheimer's disease and related disorders (ADRD). Body mass index (BMI) is the most …

Metabolic flexibility refers to the ability of tissues to adapt their use of energy sources
according to substrate availability and energy demands. This review aims to disentangle the …