Background Women are commonly prescribed a variety of medications during pregnancy.
As most organ systems are affected by the substantial anatomical and physiological …

Pregnant women have a higher risk of malaria compared to non-pregnant women. This
review provides an update on knowledge acquired since 2000 on P. falciparum and P. vivax …

Drugs can have harmful effects on the embryo or the fetus at any point during pregnancy.
Not all the damaging effects of intrauterine exposure to drugs are obvious at birth, some may …

Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Artemisinin-based combination regimens are recommended by WHO for the treatment of
uncomplicated Plasmodium falciparum malaria. One such combination comprises the …

Pregnant women are particularly vulnerable to malaria. The pharmacokinetic properties of
antimalarial drugs are often affected by pregnancy, resulting in lower drug concentrations …

Background In Africa, most plasmodium infections during pregnancy remain asymptomatic,
yet are associated with maternal anemia and low birthweight. WHO recommends intermittent …

Over the past 10 years, the available evidence on the treatment of malaria during pregnancy
has increased substantially. Owing to their relative ease of use, good sensitivity and …

Natural products have played a pivotal role in malaria chemotherapy progressing from
quinine and artemisinin to ozonide-based compounds. Many of these natural products have …

Background Dihydroartemisinin–piperaquine is an effective and well tolerated artemisinin-
based combination therapy that has been assessed extensively for the prevention and …