The MAPK pathway across different malignancies: a new perspective

M Burotto, VL Chiou, JM Lee, EC Kohn - Cancer, 2014 - Wiley Online Library
The mitogen‐activated protein kinase/extracellular signal‐regulated (MAPK/ERK) pathway
is activated by upstream genomic events and/or activation of multiple signaling events in …

Molecular pathogenesis and mechanisms of thyroid cancer

M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

[PDF][PDF] Integrated genomic characterization of papillary thyroid carcinoma

N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi… - Cell, 2014 - cell.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …

Urea derivatives in modern drug discovery and medicinal chemistry

AK Ghosh, M Brindisi - Journal of medicinal chemistry, 2019 - ACS Publications
The urea functionality is inherent to numerous bioactive compounds, including a variety of
clinically approved therapies. Urea containing compounds are increasingly used in …

Sesame inhibits cell proliferation and induces apoptosis through inhibition of STAT-3 translocation in thyroid cancer cell lines (FTC-133)

Y Ma, T Karunakaran, VP Veeraraghavan… - Biotechnology and …, 2019 - Springer
Thyroid cancer is the most widespread endocrine malignant cancer and its worldwide
occurrence rates are swiftly mounting more pressure in the research institutions. Even …

Multiparametric Photoacoustic Analysis of Human Thyroid Cancers In Vivo

J Kim, B Park, J Ha, I Steinberg, SM Hooper, C Jeong… - Cancer Research, 2021 - AACR
Thyroid cancer is one of the most common cancers, with a global increase in incidence rate
for both genders. Ultrasound-guided fine-needle aspiration is the current gold standard to …

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
Importance BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its
role in PTC-related patient mortality has not been established. Objective To investigate the …

Papillary thyroid cancer prognosis: An evolving field

S Ulisse, E Baldini, A Lauro, D Pironi, D Tripodi, E Lori… - Cancers, 2021 - mdpi.com
Simple Summary Over the last couple of decades, the prognostic stratification systems of
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …

[HTML][HTML] Diagnosis and treatment of patients with thyroid cancer

QT Nguyen, EJ Lee, MG Huang, YI Park… - American health & …, 2015 - ncbi.nlm.nih.gov
Background Thyroid cancer is the most common malignancy of the endocrine system,
representing 3.8% of all new cancer cases in the United States and is the ninth most …

[HTML][HTML] Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer

AL Ho, RK Grewal, R Leboeuf… - … England Journal of …, 2013 - Mass Medical Soc
Background Metastatic thyroid cancers that are refractory to radioiodine (iodine-131) are
associated with a poor prognosis. In mouse models of thyroid cancer, selective mitogen …