Pulmonary surfactant: an immunological perspective
Z Chroneos, Z Sever-Chroneos… - Cellular Physiology and …, 2009 - karger.com
Pulmonary surfactant has two crucial roles in respiratory function; first, as a biophysical entity
it reduces surface tension at the air water interface, facilitating gas exchange and alveolar …
it reduces surface tension at the air water interface, facilitating gas exchange and alveolar …
[HTML][HTML] CD40/CD40 ligand interactions in immune responses and pulmonary immunity
T Kawabe, M Matsushima, N Hashimoto… - Nagoya journal of …, 2011 - ncbi.nlm.nih.gov
The CD40 ligand/CD40 pathway is widely recognized for its prominent role in immune
regulation and homeostasis. CD40, a member of the tumor necrosis factor receptor family, is …
regulation and homeostasis. CD40, a member of the tumor necrosis factor receptor family, is …
Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models
M Hittinger, J Juntke, S Kletting… - Advanced drug delivery …, 2015 - Elsevier
New pharmaceutical formulations must be proven as safe and effective before entering
clinical trials. Also in the context of pulmonary drug delivery, preclinical models allow testing …
clinical trials. Also in the context of pulmonary drug delivery, preclinical models allow testing …
Modulation of immunological activity on macrophages induced by diazinon
N Ogasawara, M Matsushima, N Kawamura, K Atsumi… - Toxicology, 2017 - Elsevier
Diazinon is an organophosphorus (OP) insecticide and is widely used not only in agriculture
but also homes and garden in Japan. Diazinon has been reported to increase TNF-α …
but also homes and garden in Japan. Diazinon has been reported to increase TNF-α …
[HTML][HTML] Lung surfactant as a biophysical assay for inhalation toxicology
Lung surfactant (LS) is a mixture of lipids and proteins that forms a thin film at the gas-
exchange surfaces of the alveoli. The components and ultrastructure of LS contribute to its …
exchange surfaces of the alveoli. The components and ultrastructure of LS contribute to its …
Effects of Decreased Calmodulin Protein on the Survival Mechanisms of Alveolar Macrophages during Pneumocystis Pneumonia
ME Lasbury, PJ Durant, CP Liao, CH Lee - Infection and immunity, 2009 - Am Soc Microbiol
Pneumocystis infection causes increased intracellular levels of reactive oxygen species
(ROS) and the subsequent apoptosis of alveolar macrophages (Amø). Assessments of key …
(ROS) and the subsequent apoptosis of alveolar macrophages (Amø). Assessments of key …