Oocyte competence in women with polycystic ovary syndrome
S Palomba, J Daolio, GB La Sala - Trends in Endocrinology & Metabolism, 2017 - cell.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age and affects fertility and pregnancy in cases of oligoanovulation. Ovulation …
reproductive age and affects fertility and pregnancy in cases of oligoanovulation. Ovulation …
[HTML][HTML] HYPOXIA AND REPRODUCTIVE HEALTH: Hypoxia and ovarian function: follicle development, ovulation, oocyte maturation
M Lim, JG Thompson, KR Dunning - Reproduction, 2021 - rep.bioscientifica.com
The ovarian follicle provides the oocyte with the ideal environment for growth and
development in preparation for ovulation and fertilisation. The follicle undergoes many …
development in preparation for ovulation and fertilisation. The follicle undergoes many …
[HTML][HTML] Epigenetic dynamics during preimplantation development
In vitro maturation (IVM) offers significant benefits for human infertility treatment and animal
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
Single-cell RNA sequencing analysis of mouse follicular somatic cells
S Li, LN Chen, HJ Zhu, X Feng, FY Xie… - Biology of …, 2021 - academic.oup.com
Within the development of ovarian follicle, in addition to cell proliferation and differentiation,
sophisticated cell–cell cross talks are established among follicular somatic cells such as …
sophisticated cell–cell cross talks are established among follicular somatic cells such as …
[HTML][HTML] HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells
VS Baddela, A Sharma, M Michaelis, J Vanselow - Scientific reports, 2020 - nature.com
Abstract Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor, consisting
of a constitutively expressed β-subunit (HIF1B) and a regulated α-subunit (HIF1A). In the …
of a constitutively expressed β-subunit (HIF1B) and a regulated α-subunit (HIF1A). In the …
Bisphenol A and S impaired ovine granulosa cell steroidogenesis
O Téteau, M Jaubert, A Desmarchais… - …, 2020 - rep.bioscientifica.com
Bisphenols, plasticisers used in food containers, can transfer to food. Bisphenol A (BPA) has
been described as an endocrine disruptor and consequently banned from the food industry …
been described as an endocrine disruptor and consequently banned from the food industry …
Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus–oocyte complexes
J Guo, L Shi, X Gong, M Jiang, Y Yin… - Journal of Cell …, 2016 - journals.biologists.com
Communication between oocytes and their companion somatic cells promotes the healthy
development of ovarian follicles, which is crucial for producing oocytes that can be fertilized …
development of ovarian follicles, which is crucial for producing oocytes that can be fertilized …
Failure to launch: aberrant cumulus gene expression during oocyte in vitro maturation
In vitro maturation (ivM) offers significant benefits for human infertility treatment and animal
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
Reprogramming of glucose metabolism of cumulus cells and oocytes and its therapeutic significance
S Imanaka, H Shigetomi, H Kobayashi - Reproductive Sciences, 2022 - Springer
The aim of this review is to summarize our current understanding of the molecular
mechanism for the glucose metabolism, especially pyruvate dehydrogenase (PDH), during …
mechanism for the glucose metabolism, especially pyruvate dehydrogenase (PDH), during …
Ovarian tissue damage after grafting: systematic review of strategies to improve follicle outcomes
L Cacciottola, J Donnez, MM Dolmans - Reproductive biomedicine online, 2021 - Elsevier
Frozen-thawed human ovarian tissue endures large-scale follicle loss in the early post-
grafting period, characterized by hypoxia lasting around 7 days. Tissue revascularization …
grafting period, characterized by hypoxia lasting around 7 days. Tissue revascularization …