Advances in genomic data and biomarkers: revolutionizing NSCLC diagnosis and treatment

JC Restrepo, D Dueñas, Z Corredor, Y Liscano - Cancers, 2023 - mdpi.com
Simple Summary In the field of non-small cell lung cancer (NSCLC), there have been
significant advancements in genomic data and bioinformatics tools, which have improved …

Structure and functions of HMGB2 protein

T Starkova, A Polyanichko, AN Tomilin… - International Journal of …, 2023 - mdpi.com
High-Mobility Group (HMG) chromosomal proteins are the most numerous nuclear non-
histone proteins. HMGB domain proteins are the most abundant and well-studied HMG …

Genetics, genomics and emerging molecular therapies of pancreatic cancer

J Liu, M Mroczek, A Mach, M Stępień, A Aplas… - Cancers, 2023 - mdpi.com
Simple Summary This review article is a summary of the current state of knowledge
regarding the genetics of pancreatic cancer and a presentation of possible treatment options …

The neurological and non-neurological roles of the primary microcephaly-associated protein ASPM

X Wu, Z Li, ZQ Wang, X Xu - Frontiers in neuroscience, 2023 - frontiersin.org
Primary microcephaly (MCPH), is a neurological disorder characterized by small brain size
that results in numerous developmental problems, including intellectual disability, motor and …

Features of metabolism associated molecular patterns in pancreatic ductal adenocarcinoma

J Chen, Y Wang, H Jiang - Cancer Gene Therapy, 2023 - nature.com
Exploring pancreatic ductal adenocarcinoma (PDAC) metabolic landscape would contribute
to further understand PDAC from the metabolic perspective and provide more details for …

Neuroinflammation and Schizophrenia: New Therapeutic Strategies through Psychobiotics, Nanotechnology, and Artificial Intelligence (AI)

FEC Mosquera, MC Guevara-Montoya… - Journal of Personalized …, 2024 - mdpi.com
The prevalence of schizophrenia, affecting approximately 1% of the global population,
underscores the urgency for innovative therapeutic strategies. Recent insights into the role …

Incorporating genetic similarity of auxiliary samples into eGene identification under the transfer learning framework

S Zhang, Z Jiang, P Zeng - Journal of Translational Medicine, 2024 - Springer
Background The term eGene has been applied to define a gene whose expression level is
affected by at least one independent expression quantitative trait locus (eQTL). It is both …

Management of Metastatic Pancreatic Cancer—Comparison of Global Guidelines over the Last 5 Years

M Pajewska, O Partyka, A Czerw, A Deptała, E Cipora… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer (PC) is a disease with a poor prognosis due to several
factors, such as late diagnosis at an advanced stage of the disease, metastases and …

[HTML][HTML] Biological functions and therapeutic potential of SHCBP1 in human cancer

Y Lin, H Cai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The incidence of cancer is increasing globally, and it is the most common cause of death.
The identification of novel cancer diagnostic and prognostic biomarkers is important for …

Eg5 and Diseases: From the Well‐Known Role in Cancer to the Less‐Known Activity in Noncancerous Pathological Conditions

A Ricci, S Carradori, A Cataldi… - Biochemistry Research …, 2024 - Wiley Online Library
Eg5 is a protein encoded by KIF11 gene and is primarily involved in correct mitotic cell
division. It is also involved in nonmitotic processes such as polypeptide synthesis, protein …