Birth defects resulting from diabetic pregnancy are associated with apoptosis of a critical
mass of progenitor cells early during the formation of the affected organ (s). Insufficient …

Murine preimplantation embryos exposed to hyperglycemia experience decreased glucose
transport, and overexpression of the proapoptotic protein BAX, leading to increased …

Context This review presents an up-to-date summary on management of type 1 diabetes
mellitus (T1DM) among women of reproductive age and covers the following time periods …

Objective Both oxidative stress and endoplasmic reticulum stress (ER stress) are causal
events in diabetic embryopathy. We tested whether oxidative stress causes ER stress. Study …

The perinatologists are emerging as the physicians who evaluate and treat women with
recurrent pregnancy loss. Recurrent miscarriage, previously referred to as habitual abortion …

Nearly 4% of pregnant women in the United States are diabetic. Of those, 88% have
gestational diabetes and 12% have pre-existing diabetes [1]. Because the outcome of …

OBJECTIVE: The purpose of the current study was to determine whether a dietary source of
arachidonic acid could serve as a pharmacologic prophylaxis to obviate the teratogenic …

The study aimed to determine whether a consistent dose-response association can be
demonstrated, after adjustment for maternal age and White classification, between …

Congenital malformations are the leading cause of death in infants of insulin-dependent
diabetic mothers. Although there are data to suggest that hyperglycemia itself is teratogenic …

BACKGROUND Diabetic pregnancy is still associated with an increased rate of congenital
malformations despite extensive clinical efforts to normalize the risk for the offspring. The …