As the organ with the highest demand for oxygen, the brain has a poor tolerance to ischemia
and hypoxia. Despite severe ischemia/hypoxia induces the occurrence and development of …

The benefits of remote ischaemic conditioning (RIC) have been difficult to translate to
humans, when considering traditional outcome measures, such as mortality and heart …

Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …

Nature has endowed gaseous molecules such as O 2, CO 2, CO, NO, H 2 S, and N 2 with
critical and diverse roles in sustaining life, from supplying energy needed to power life and …

Remote ischemic conditioning (RIC) is a promising therapeutic approach for ischemic stroke
patients. It has been proven that RIC reduces infarct size and improves functional outcomes …

Exercise preconditioning has attracted extensive attention to induce endogenous
neuroprotection and has become the hotspot in neurotherapy. The training exercise is given …

Abstract Treatment of acute ischemic stroke with the recombinant tissue plasminogen
activator (rtPA) is associated with increased blood–brain barrier (BBB) disruption and …

Stroke is one of the main causes of neurological disability worldwide and the second cause
of death in people over 65 years old, resulting in great economic and social burden …

Alisol A, a triterpene isolated from Alisma Orientale, has been shown to exhibit anti-
inflammatory effects and vascular protection. This study was designed to observe the effect …

Background A blockage in a blood vessel can cause reduced blood flow to the brain, which
eventually leads to the death of surrounding tissue. Several studies have attempted to …