Flavonoids as natural phenolic compounds and their role in therapeutics: An overview

RE Mutha, AU Tatiya, SJ Surana - Future journal of pharmaceutical …, 2021 - Springer
Background Natural plants and plant-derived formulations have been used by mankind from
the ancient period of time. For the past few years, many investigations elaborated the …

Influence of resveratrol on the immune response

L Malaguarnera - Nutrients, 2019 - mdpi.com
Resveratrol is the most well-known polyphenolic stilbenoid, present in grapes, mulberries,
peanuts, rhubarb, and in several other plants. Resveratrol can play a beneficial role in the …

Stilbene-based natural compounds as promising drug candidates against COVID-19

HM Wahedi, S Ahmad, SW Abbasi - Journal of Biomolecular …, 2021 - Taylor & Francis
The pandemic coronavirus disease (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) presents a great threat to public health. Currently …

SIRT1 activation by natural phytochemicals: an overview

C Iside, M Scafuro, A Nebbioso, L Altucci - Frontiers in pharmacology, 2020 - frontiersin.org
Sirtuins are class III histone deacetylases, whose enzymatic activity is dependent on NAD+
as a cofactor. Sirtuins are reported to modulate numerous activities by controlling gene …

Lignin monomers from beyond the canonical monolignol biosynthetic pathway: another brick in the wall

JC del Río, J Rencoret, A Gutiérrez… - ACS Sustainable …, 2020 - ACS Publications
Lignin is conventionally defined as being formed by the oxidative polymerization of three
main monolignols, p-coumaryl alcohol, coniferyl alcohol, and sinapyl alcohol, that are …

Biological activities of stilbenoids

BC Akinwumi, KAM Bordun, HD Anderson - International journal of …, 2018 - mdpi.com
Stilbenoids are a group of naturally occurring phenolic compounds found in various plant
species. They share a common backbone structure known as stilbene, but differ in the …

[HTML][HTML] Progress to improve oral bioavailability and beneficial effects of resveratrol

A Chimento, F De Amicis, R Sirianni… - International journal of …, 2019 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxystilbene; RSV) is a natural nonflavonoid polyphenol present
in many species of plants, particularly in grapes, blueberries, and peanuts. Several in vitro …

Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance

S Mirzaei, AT Mohammadi, MH Gholami… - Pharmacological …, 2021 - Elsevier
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

The potential use of plant natural products and plant extracts with antioxidant properties for the prevention/treatment of neurodegenerative diseases: in vitro, in vivo …

F Pohl, P Kong Thoo Lin - Molecules, 2018 - mdpi.com
Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and
Huntington's disease, present a major health issue and financial burden for health care …

Formation and biological targets of quinones: cytotoxic versus cytoprotective effects

JL Bolton, T Dunlap - Chemical research in toxicology, 2017 - ACS Publications
Quinones represent a class of toxicological intermediates, which can create a variety of
hazardous effects in vivo including, acute cytotoxicity, immunotoxicity, and carcinogenesis …