Exposure of eukaryotic cells to ionizing radiation (IR) results in the immediate formation of
free radicals that last a matter of milliseconds. It has been assumed that the subsequent …

Ionizing radiation, like a variety of other cellular stress factors, can activate or down-regulate
multiple signaling pathways, leading to either increased cell death or increased cell …

Monomers are released from dental resin materials, and thus cause adverse biological
effects in mammalian cells. Cytotoxicity and genotoxicity of some of these methacrylates …

purpose. To evaluate whether experimentally induced dry eye in mice activates mitogen-
activated protein kinase (MAPK) signaling pathways, c-Jun N-terminal kinases (JNK) …

The threat of radiation-induced late normal tissue injury limits the dose of radiation that can
be delivered safely to cancer patients presenting with solid tumors. Tissue dysfunction and …

Radiation rapidly and persistently alters the soluble and insoluble components of the tissue
microenvironment. This affects the cell phenotype, tissue composition and the physical …

Liver fibrosis represents a significant health problem worldwide of which no acceptable
therapy exists. The most characteristic feature of liver fibrosis is excess deposition of type I …

Reactive oxygen species (ROS) are the more abundant free radicals in nature and have
been related with a number of tissue/organ injuries induced by xenobiotics, ischemia …

There is a growing body of evidence documenting probiotic bacteria to have a beneficial
effect to the host through their ability to modulate the mucosal immune system. Many …

Radiation-induced lung fibrosis (RILF) is a severe side effect of radiotherapy in lung cancer
patients that presents as a progressive pulmonary injury combined with chronic …