Male breast cancer: an update

S Fox, V Speirs, AM Shaaban - Virchows Archiv, 2022 - Springer
Male breast cancer (MBC) is rare, accounting for less than 1% of all breast cancer but the
incidence has increased worldwide. Risk factors include increased longevity, obesity …

Defining genomic, transcriptomic, proteomic, epigenetic, and phenotypic biomarkers with prognostic capability in male breast cancer: a systematic review

S Chatterji, E Krzoska, CW Thoroughgood… - The Lancet …, 2023 - thelancet.com
Although similar phenotypically, there is evidence that male and female breast cancer differ
in their molecular landscapes. In this systematic review, we consolidated all existing …

[HTML][HTML] Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer

S Chatterji, JM Niehues, M van Treeck… - NPJ Breast …, 2023 - nature.com
Breast cancer prognosis and management for both men and women are reliant upon
estrogen receptor alpha (ERα) and progesterone receptor (PR) expression to inform …

[HTML][HTML] HR+/HER2− de novo metastatic breast cancer: a true peculiar entity?

R Torrisi, F Jacobs, C Miggiano, R De Sanctis… - Drugs in …, 2023 - ncbi.nlm.nih.gov
De novo metastatic breast cancer (dnMBC) accounts for~ 6–10% of all breast cancers and
for~ 30% of MBC with increasing incidence over time. Hormone receptor-positive/human …

Mortality Risks Over 20 Years in Men With Stage I to III Hormone Receptor–Positive Breast Cancer

J Leone, MJ Hassett, RA Freedman, SM Tolaney… - JAMA …, 2024 - jamanetwork.com
Importance In women with hormone receptor–positive (HR+) breast cancer, the risk of
distant recurrence and death persists for at least 20 years from diagnosis. The risk of late …

Efficacy of neoadjuvant chemotherapy in male breast cancer compared with female breast cancer

JP Leone, MJ Hassett, J Leone, SM Tolaney… - Cancer, 2022 - Wiley Online Library
Background Neoadjuvant chemotherapy (NAC) is standard for many females with breast
cancer (FBC). The efficacy of NAC in male breast cancer (MaBC) is unclear. The aim of this …

[HTML][HTML] Clinicopathological features of male patients with breast cancer based on a nationwide registry database in Japan

A Shimomura, M Nagahashi, H Kumamaru, K Aogi… - Breast Cancer, 2022 - Springer
Background Male breast cancer (MBC) is rare; however, its incidence is increasing. There
have been no large-scale reports on the clinicopathological characteristics of MBC in Japan …

Survival in male breast cancer over the past 3 decades

JP Leone, RA Freedman, J Leone… - JNCI: Journal of the …, 2023 - academic.oup.com
Background Breast cancer mortality in women has declined statistically significantly over the
past several years. In men, it is unclear whether survival has changed over time. We …

Proton Therapy in the Treatment of Men with Breast Cancer

JA Bradley, J Gracie… - … Journal of Particle …, 2023 - meridian.allenpress.com
Purpose Male breast cancer treatment involves multimodality therapy, including radiation
therapy; nevertheless, few men have received proton therapy (PT) for it. Further, heart …

[HTML][HTML] Gender minorities in breast cancer–Clinical trials enrollment disparities: Focus on male, transgender and gender diverse patients

F Miglietta, L Pontolillo, C De Angelis, R Caputo… - The Breast, 2024 - Elsevier
Background The last years have seen unprecedented improvement in breast cancer (BC)
survival rates. However, this entirely apply to female BC patients, since gender minorities …