[HTML][HTML] Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets
S Zhang, X Xiao, Y Yi, X Wang, L Zhu, Y Shen… - … and Targeted Therapy, 2024 - nature.com
Tumorigenesis is a multistep process, with oncogenic mutations in a normal cell conferring
clonal advantage as the initial event. However, despite pervasive somatic mutations and …
clonal advantage as the initial event. However, despite pervasive somatic mutations and …
Use of Virus Genotypes in Machine Learning Diagnostic Prediction Models for Cervical Cancer in Women With High-Risk Human Papillomavirus Infection
T Xiao, C Wang, M Yang, J Yang, X Xu… - JAMA Network …, 2023 - jamanetwork.com
Importance High-risk human papillomavirus (hrHPV) is recognized as an etiologic agent for
cervical cancer, and hrHPV DNA testing is recommended as the preferred method of …
cervical cancer, and hrHPV DNA testing is recommended as the preferred method of …
[HTML][HTML] Mathematical Modelling of Cervical Precancerous Lesion Grade Risk Scores: Linear Regression Analysis of Cellular Protein Biomarkers and Human Papillomavirus E6 …
S Bumrungthai, T Ekalaksananan, P Kleebkaow… - Diagnostics, 2023 - mdpi.com
The current practice of determining histologic grade with a single molecular biomarker can
facilitate differential diagnosis but cannot predict the risk of lesion progression. Cancer is …
facilitate differential diagnosis but cannot predict the risk of lesion progression. Cancer is …
[HTML][HTML] Using online search activity for earlier detection of gynaecological malignancy
Background Ovarian cancer is the most lethal and endometrial cancer the most common
gynaecological cancer in the UK, yet neither have a screening program in place to facilitate …
gynaecological cancer in the UK, yet neither have a screening program in place to facilitate …
[HTML][HTML] Evaluating the feasibility of machine-learning-based predictive models for precancerous cervical lesions in patients referred for colposcopy
M Chen, J Wang, P Xue, Q Li, Y Jiang, Y Qiao - Diagnostics, 2022 - mdpi.com
Background: Colposcopy plays an essential role in cervical cancer control, but its
performance remains unsatisfactory. This study evaluates the feasibility of machine learning …
performance remains unsatisfactory. This study evaluates the feasibility of machine learning …
[HTML][HTML] Developing a predictive nomogram for colposcopists: a retrospective, multicenter study of cervical precancer identification in China
P Xue, S Seery, S Wang, Y Jiang, Y Qiao - BMC cancer, 2023 - Springer
Background Colposcopic examination with biopsy is the standard procedure for referrals
with abnormal cervical cancer screening results; however, the decision to biopsy is …
with abnormal cervical cancer screening results; however, the decision to biopsy is …