Ischemia–Reperfusion Injury: Molecular Mechanisms of Pathogenesis and Methods of Their Correction
RG Goncharov, MG Sharapov - Molecular Biology, 2023 - Springer
Ischemia–reperfusion is a cascade of complex and interrelated pathological processes
underlying many human diseases, including such socially significant diseases as stroke …
underlying many human diseases, including such socially significant diseases as stroke …
The molecular mechanism involved in cardioprotection by the dietary flavonoid fisetin as an agonist of PPAR-γ in a murine model of myocardial infarction
S Garg, SI Khan, RK Malhotra, MK Sharma… - Archives of biochemistry …, 2020 - Elsevier
The methodology exploring the cardioprotective potential of the flavonoid Fisetin through its
ability to modulate PPAR-γ was unraveled in the present study. Computational modelling …
ability to modulate PPAR-γ was unraveled in the present study. Computational modelling …
Luteolin Pretreatment Ameliorates Myocardial Ischemia/Reperfusion Injury by lncRNA‐JPX/miR‐146b Axis
T Xu, Y Zhang, G Liao, H Xuan, J Yin… - Analytical Cellular …, 2023 - Wiley Online Library
Background. In the present study, we aimed to find out whether luteolin (Lut) pretreatment
could ameliorate myocardial ischemia/reperfusion (I/R) injury by regulating the lncRNA just …
could ameliorate myocardial ischemia/reperfusion (I/R) injury by regulating the lncRNA just …
Coronary Endothelium No‐Reflow Injury Is Associated with ROS‐Modified Mitochondrial Fission through the JNK‐Drp1 Signaling Pathway
Y Chen, C Liu, P Zhou, J Li, X Zhao… - Oxidative Medicine …, 2021 - Wiley Online Library
Coronary artery no‐reflow is a complex problem in the area of reperfusion therapy, and the
molecular mechanisms underlying coronary artery no‐reflow injury have not been fully …
molecular mechanisms underlying coronary artery no‐reflow injury have not been fully …
[Retracted] LATS2 Deletion Attenuates Myocardial Ischemia‐Reperfusion Injury by Promoting Mitochondrial Biogenesis
Y Chen, C Liu, J Li, P Zhou, X Zhao… - Oxidative Medicine …, 2021 - Wiley Online Library
Reperfusion therapy is the most effective treatment for acute myocardial infarction, but it can
damage cardiomyocytes through a mechanism known as myocardial ischemia/reperfusion …
damage cardiomyocytes through a mechanism known as myocardial ischemia/reperfusion …
Bevacizumab‐induced mitochondrial dysfunction, endoplasmic reticulum stress, and ERK inactivation contribute to cardiotoxicity
Y Li, W Tian, D Yue, C Chen, C Li… - … Medicine and Cellular …, 2021 - Wiley Online Library
The molecular mechanisms underlying the cardiotoxicity associated with bevacizumab, a
first‐line immunotherapeutic agent used to treat lung cancer, are not fully understood. Here …
first‐line immunotherapeutic agent used to treat lung cancer, are not fully understood. Here …
[HTML][HTML] Levosimendan in rats decreases acute kidney injury after cardiopulmonary resuscitation by improving mitochondrial dysfunction
L Zhao, L Tian, S Wang, W Yang, X Lu… - … Andrology and Urology, 2021 - ncbi.nlm.nih.gov
Background Acute kidney injury (AKI), the most common complication after cardiac
resuscitation, is highly prevalent and harmful. There is increasing evidence that …
resuscitation, is highly prevalent and harmful. There is increasing evidence that …
Shenlian extract decreases mitochondrial autophagy to regulate mitochondrial function in microvascular to alleviate coronary artery no‐reflow
JJ Li, YJ Wang, CM Wang, YJ Li, Q Yang… - Phytotherapy …, 2023 - Wiley Online Library
Shenlian (SL) extract has been proven to be effective in the prevention and treatment of
atherosclerosis and myocardial ischemia. However, the function and molecular mechanisms …
atherosclerosis and myocardial ischemia. However, the function and molecular mechanisms …
Acetylcholine exerts cytoprotection against hypoxia/reoxygenation-induced apoptosis, autophagy and mitochondrial impairment through both muscarinic and nicotinic …
Acetylcholine (ACh) has been shown to exert cardioprotection against myocardial
ischemia/reperfusion (I/R) injury. However, whether ACh exerts its cardioprotection …
ischemia/reperfusion (I/R) injury. However, whether ACh exerts its cardioprotection …
LP342, a novel histone deacetylase inhibitor, decreases nitro-oxidative stress, mitochondrial dysfunction and hepatic ischaemia/reperfusion injury in mice
DJ Samuvel, Y Krishnasamy, L Li… - RPS Pharmacy and …, 2023 - academic.oup.com
Objectives Some histone deacetylase (HDAC) isoforms contribute to ischaemia/reperfusion
(IR) injury (IRI). Here, we examined whether LP342, the lead candidate of a new generation …
(IR) injury (IRI). Here, we examined whether LP342, the lead candidate of a new generation …