Targeting gut microbiota in aging-related cardiovascular dysfunction: Focus on the mechanisms

S Liu, Y He, Y Zhang, Z Zhang, K Huang, L Deng… - Gut …, 2023 - Taylor & Francis
The global population is aging and age-related cardiovascular disease is increasing. Even
after controlling for cardiovascular risk factors, readmission and mortality rates remain high …

[HTML][HTML] Advances in the integration of metabolomics and metagenomics for human gut microbiome and their clinical applications

F Puig-Castellví, R Pacheco-Tapia, M Deslande… - TrAC Trends in …, 2023 - Elsevier
The human microbiome and its metabolic output play an important role in shaping human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …

Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity

SC Raju, A Molinaro, A Awoyemi, SF Jørgensen… - Genome Medicine, 2024 - Springer
Background Interactions between the gut microbiota, diet, and host metabolism contribute to
the development of cardiovascular disease, but a firm link between disease-specific gut …

Gut Microbiota alterations and circulating imidazole propionate levels are associated with obstructive coronary artery disease in people with HIV

M Trøseid, A Molinaro, M Gelpi, B Vestad… - The Journal of …, 2024 - academic.oup.com
Background The impact of gut microbiota and its metabolites on coronary artery disease
(CAD) in people with human immunodeficiency virus (PWH) is unknown. Emerging …

The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum

M Byndloss, S Devkota, F Duca, JH Niess… - Diabetes, 2024 - diabetesjournals.org
This article summarizes the state of the science on the role of the gut microbiota (GM) in
diabetes from a recent international expert forum organized by Diabetes, Diabetes Care …

[HTML][HTML] Gut microbiota-generated metabolites: missing puzzles to hosts' health, diseases, and aging

Y Zhang, S Wei, H Zhang, Y Jo, JS Kang, KT Ha… - BMB …, 2024 - ncbi.nlm.nih.gov
The gut microbiota, an intricate community of bacteria residing in the gastrointestinal system,
assumes a pivotal role in various physiological processes. Beyond its function in food …

Gut microbiome and cardiometabolic comorbidities in people living with HIV

M Trøseid, SD Nielsen, I Vujkovic-Cvijin - Microbiome, 2024 - Springer
Background Despite modern antiretroviral therapy (ART), people living with HIV (PLWH)
have increased relative risk of inflammatory-driven comorbidities, including cardiovascular …

Bifidobacterium alleviate metabolic disorders via converting methionine to 5'-methylthioadenosine

Q Lyu, RA Chen, HL Chuang, HB Zou, L Liu… - Gut …, 2024 - Taylor & Francis
Dietary patterns and corresponding gut microbiota profiles are associated with various
health conditions. A diet rich in polyphenols, primarily plant-based, has been shown to …

Gut microbiota's causative relationship with peripheral artery disease: a Mendelian randomization study

Y Tian, G Yao, L Skudder-Hill, G Xu, Y Qian… - Frontiers in …, 2024 - frontiersin.org
Introduction The relationship between gut microbiota and peripheral artery disease (PAD)
remains understudied. While traditional risk factors like smoking and hyperlipidemia are well …

Microbial imidazole propionate affects glomerular filtration rate in patients with diabetic nephropathy through association with HSP90α

D Lv, W Zheng, Z Zhang, Z Lin, K Wu, H Liu… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Imidazole propionate (ImP) is a detrimental metabolite produced by the fermentation of
histidine intermediates via the intestinal flora. Here, the untargeted metabolite analysis of …