Abstract Transient Receptor Potential Vanilloid 4 (TRPV4) is a broadly expressed,
polymodally gated ion channel that plays an important role in many physiological and …

Background: Sepsis is defined as systemic inflammatory response syndrome (SIRS) in the
context of an underlying infectious process, and is associated with high rates of morbidity …

Sepsis, the systemic inflammatory response to infection, represents the major cause of death
in critically ill veterinary patients. Whereas important advances in our understanding of the …

Sepsis is one of the leading causes of death in the critically ill. Early diagnosis is important to
avoid delay in instituting appropriate treatment. However, diagnosis can be delayed …

Rationale Sepsis is a common cause of death in the intensive care unit with mortality up to
70% when accompanied by multiple organ dysfunction. Rapid diagnosis and the institution …

Sepsis is a complex clinical syndrome triggered by an inflammatory host response to an
infection. It is usually complicated to detect and diagnose, and has severe consequences in …

Background: Sepsis-induced inflammation in the gut/peritoneal compartment occurs early in
sepsis and can lead to acute lung injury (ALI). We have suggested that inflammatory ascites …

The possibility that inflammation plays a causal role in major depression is an important
claim in the emerging field of immunopsychiatry and has generated hope for new …

This study aimed to investigate the possible relationship between the two biomarkers
presepsin and procalcitonin (PCT) and monocyte immune function, and to explore their …

Background Sepsis, a life-threatening condition resulting from uncontrolled host responses
to infection, poses a global health challenge with limited therapeutic options. Due to high …