The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Etiology, transmission and protection: Neisseria gonorrhoeae (the gonococcus) is the
etiological agent for the strictly human sexually transmitted disease gonorrhea. Infections …

The Centers for Disease Control and the World Health Organization have issued a list of
priority pathogens for which there are dwindling therapeutic options, including antibiotic …

Background The vaginal microbiota can impact the susceptibility of women to bacterial
vaginosis (BV) and sexually transmitted infections (STIs). BV is characterized by depletion of …

Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

Thirteen percent of pregnancies result in preterm birth or stillbirth, accounting for fifteen
million preterm births and three and a half million deaths annually. A significant cause of …

Pathogenesis of Neisseria gonorrhoeae in the female reproduc... : Current Opinion in
Hematology Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract …

OBJECTIVE: An inflammatory challenge disrupts the cervical epithelial barrier and promotes
cervical remodeling. STUDY DESIGN: Immortalized ectocervical and endocervical cells …

OBJECTIVE: Clinically, vaginal progesterone (VP) and 17 alpha-hydroxyprogesterone
caproate (17P) have been shown to prevent preterm birth (PTB) in high-risk populations. We …

The alarming rise of antibiotic resistance and the emergence of new vaccine technologies
have increased the focus on vaccination to control gonorrhea. Neisseria gonorrhoeae …