Splenic lymphocytes from cytomegalovirus-infected mice lost their in vitro proliferative
responses to cytomegalovirus antigen within 3 h after in vivo treatment with antilymphocyte …

Abstract BALB/c and C57BL/6 mice were infected with murine cytomegalovirus (MCMV). On
day4 or 12 of the infection, the animals were immunized with SRBC (T-dependent), TNP …

Mice fed a basal diet which contained 0.018% ciclosporin (CsA) achieved
immunosuppressive blood levels of 1,400–2,200 ng/ml. Observations for 84 days of mice …

Both human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) are widespread in the
population. They can cause severe morbidity and mortality, especially in …

The term interferon (IFN) was first used by Isaacs and Lindenmann in 1957 to describe a
factor, present in the supernatant of cultured chick chorioallantoic membranes previously …

The first description of a local delayed-type hypersen-sitivity (DTH) reaction dates as far
back as 1798, when E. Jenner commented on the response following the cutaneous …

Despite progress in our understanding of the acquired immunodeficiency syndrome (AIDS),
many central questions regarding pathogenesis remain unanswered (1). Early attention in …

The purpose of this article is to discuss factors which may contribute to the persistance of
cytomegalovirus (CMV) infection in the face of host responses. In general, available …

The International Committee on Taxonomy of Viruses (ICTV) classifies herpesviruses in the
order Herpesvirales (MQ and King, 2012; Taxonomy). Herpesviruses are further classified …

Under most circumstances there is no grossly visible lesion. During acute, generalized
infections in mice, the liver may be enlarged and pale with hemorrhagic foci. Intestinal …