The Poly (ADP-ribose) polymerase (PARP) family has many essential functions in cellular
processes, including the regulation of transcription, apoptosis and the DNA damage …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of cancer with a dismal
prognosis. The lack of symptoms in the early phase of the disease makes early diagnosis …

Simple Summary In pancreatic cancer, immunotherapy and targeted therapies have not
brought about the therapeutic revolution that has been observed in other malignancies …

Pancreatic cancer is a devastating and lethal human malignancy with no curable chemo-
treatments available thus far. More than 90% of pancreatic tumors are formed from ductal …

Cancers are the leading cause of death worldwide. The most common cancers include
breast, lung, and colorectum. Salivary metabolome profiling is a novel non-invasive method …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal cancers with a dismal
prognosis for the patient. This is due to limited diagnostic options for the early detection of …

Background Pancreatic cancer (PC) is a highly lethal malignancy regarding digestive
system, which is the fourth leading factor of cancer-related mortalities in the globe …

In 90% of pancreatic ductal adenocarcinoma cases, genetic alteration of the proto-oncogene
Kras has occurred, leading to uncontrolled proliferation of cancerous cells. Targeting Kras …

The numerous biological barriers, which limit pharmacotherapy of pancreatic carcinoma,
including inadequate drug accumulation in the tumor environment, a dense extracellular …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with
almost no curative chemotherapeutic treatment. Besides the development of new …