Drug delivery systems in HIV pharmacotherapy: what has been done and the challenges standing ahead

A Sosnik, DA Chiappetta, ÁM Carcaboso - Journal of Controlled release, 2009 - Elsevier
Worldwide, over 40 million people are infected with the Human Immunodeficiency Virus
(HIV). The High Activity Antiretroviral Therapy (HAART) combines at least three antiretroviral …

Herbal medicines for treating HIV infection and AIDS

JP Liu, E Manheimer, M Yang - Cochrane Database of …, 2005 - cochranelibrary.com
Background HIV‐infected people and AIDS patients often seek complementary therapies
including herbal medicines due to reasons such as unsatisfactory effects, high cost, non …

Delavirdine: a review of its use in HIV infection

LJ Scott, CM Perry - Drugs, 2000 - Springer
Delavirdine | Drugs Skip to main content SpringerLink Account Menu Find a journal Publish
with us Track your research Search Cart 1.Home 2.Drugs 3.Article Delavirdine A Review of its …

Development of topical microbicides to prevent the sexual transmission of HIV

RW Buckheit Jr, KM Watson, KM Morrow, AS Ham - Antiviral research, 2010 - Elsevier
Women comprise almost 50% of the population of people living with HIV and the majority of
these women contracted the virus through sexual transmission in monogamous …

Recombinant rabies virus as potential live-viral vaccines for HIV-1

MJ Schnell, HD Foley, CA Siler… - Proceedings of the …, 2000 - National Acad Sciences
Recombinant, replication-competent rabies virus (RV) vaccine strain-based vectors were
developed expressing HIV type I (HIV-1) envelope glycoprotein (gp160) from both a …

Considerations and development of topical microbicides to inhibit the sexual transmission of HIV

JA Turpin - Expert opinion on investigational drugs, 2002 - Taylor & Francis
The increased incidence of HIV/AIDS disease in women aged 15–49 years has identified
the urgent need for a female-controlled, efficacious and safe vaginal topical microbicide. To …

Targeting HIV-1 integrase with strand transfer inhibitors

Y Li, S Xuan, Y Feng, A Yan - Drug Discovery Today, 2015 - Elsevier
Highlights•Overview of structural and functional properties of HIV-1 integrase
(IN).•Classifying the HIV-1 integrase strand transfer inhibitors (INSTIs) into ten …

Initiation and continuation of newer antiretroviral treatments among medicaid recipients with AIDS

S Crystal, U Sambamoorthi… - Journal of general …, 2001 - Wiley Online Library
OBJECTIVE: To examine initiation of newer antiretroviral treatments across
sociodemographic subgroups during the 3 years following the introduction of these …

Optimal drug cocktail design: methods for targeting molecular ensembles and insights from theoretical model systems

ML Radhakrishnan, B Tidor - Journal of chemical information and …, 2008 - ACS Publications
Drug resistance is a significant obstacle in the effective treatment of diseases with rapidly
mutating targets, such as AIDS, malaria, and certain forms of cancer. Such targets are …

TSG101: a novel anti-HIV-1 drug target

H Chen, X Liu, Z Li, P Zhan… - Current medicinal …, 2010 - ingentaconnect.com
The life cycle of HIV-1 requires extensive assistance from the host cell proteins and
pathways. TSG101 is one of the cellular proteins involved in the budding process of HIV-1 …