It has been 50 years since Francis Fontan pioneered the operation that today bears his
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …

Surgical innovation and multidisciplinary management have allowed children born with
univentricular physiology congenital heart disease to survive into adulthood. An estimated …

The past 60 years have brought remarkable advancements in the diagnosis and treatment of
congenital heart disease (CHD). Early diagnosis and improvements in cardiac surgery and …

The Fontan procedure has led to increased long-term survival of patients with single
ventricle congenital heart disease. Hemodynamic changes associated with the Fontan …

Life expectancy and quality of life for those born with congenital heart disease (CHD) have
greatly improved over the past 3 decades. While representing a great advance for these …

Over the past decade, as the majority of patients with single ventricle anatomy who have
undergone the Fontan operation reach adulthood, a newly recognized disease process …

Aims Liver fibrosis and cirrhosis are a consequence of a Fontan physiology, and determine
prognosis. It is unclear whether non-invasive assessment of liver pathology is helpful to …

Background Despite an ageing Fontan population, data on late outcomes are still scarce.
Reported outcome measures and determinants vary greatly between studies making …

Abstract Aims The Fontan operation has resulted in improved survival in patients with single‐
ventricle congenital heart disease. As a result, there is a growing population of teenagers …

Objectives Liver disease is an important contributor to morbidity and mortality in patients
after Fontan surgery. There has been no large-scale survey of liver health in this population …