The multifaceted role of curcumin in advanced nanocurcumin form in the treatment and management of chronic disorders

P Tagde, P Tagde, F Islam, S Tagde, M Shah… - Molecules, 2021 - mdpi.com
Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of
therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic …

A review of the role of curcumin in metal induced toxicity

E Smirnova, M Moniruzzaman, S Chin, A Sureshbabu… - Antioxidants, 2023 - mdpi.com
Metal toxicity poses a potential global threat to the environment and living beings. Their
numerous agricultural, medical, industrial, domestic, and technological applications result in …

Heavy metal mediated progressive degeneration and its noxious effects on brain microenvironment

L Murumulla, LJM Bandaru, S Challa - Biological Trace Element Research, 2024 - Springer
Heavy metals, including lead (Pb), cadmium (Cd), arsenic (As), cobalt (Co), copper (Cu),
manganese (Mn), zinc (Zn), and others, have a significant impact on the development and …

Copper homeostasis and cuproptosis in mitochondria

Z Tian, S Jiang, J Zhou, W Zhang - Life Sciences, 2023 - Elsevier
Mitochondria serve as sites for energy production and are essential for regulating various
forms of cell death induced by metal metabolism, targeted anticancer drugs, radiotherapy …

Heavy metal accumulation, tissue injury, oxidative stress, and inflammation in dromedary camels living near petroleum industry sites in Saudi Arabia

JS Ajarem, AK Hegazy, GA Allam, AA Allam… - Animals, 2022 - mdpi.com
Simple Summary The petroleum industry is a major source of energy and economic
development but can pollute the environment and negatively impact animal and human …

Nano-curcumin prevents copper reproductive toxicity by attenuating oxidative stress and inflammation and improving Nrf2/HO-1 signaling and pituitary-gonadal axis in …

WS Sarawi, AM Alhusaini, LM Fadda, HA Alomar… - Toxics, 2022 - mdpi.com
Copper is essential for several cellular processes and is an important catalytic factor for
many proteins. However, excess copper can provoke oxidative stress and reproductive …

The synergistic effect of nanocurcumin and donepezil on Alzheimer's via PI3K/AKT/GSK-3β pathway modulating

DM Beltagy, NF Nawar, TM Mohamed… - Prostaglandins & Other …, 2024 - Elsevier
Alzheimer's disease (AD) hallmarks include amyloid-βeta (Aβ) and tau proteins aggregates,
neurite degeneration, microglial activation with cognitive impairment. Phosphatidylinositol-3 …

β-Carotene extracted from Blakeslea trispora attenuates oxidative stress, inflammatory, hepatic injury and immune damage induced by copper sulfate in zebrafish …

Y Wang, J Lu, H Qu, C Cai, H Liu, J Chu - Comparative Biochemistry and …, 2022 - Elsevier
Abstract β-Carotene, as a kind of potent antioxidant compounds, has gained extensive
attention. Blakeslea trispora, a filiform aerobic fungus, has been proposed as a natural …

Inflammation in Metal-Induced Neurological Disorders and Neurodegenerative Diseases

R Wei, P Wei, H Yuan, X Yi, M Aschner… - Biological Trace Element …, 2024 - Springer
Essential metals play critical roles in maintaining human health as they participate in various
physiological activities. Nonetheless, both excessive accumulation and deficiency of these …

Therapeutic potential of Aloe vera-coated curcumin encapsulated nanoparticles in an Alzheimer-induced mice model: behavioural, biochemical and histopathological …

P Sharma, P Kumari, M Sharma, R Sharma… - Journal of …, 2024 - Taylor & Francis
Objective The main purpose of the present study was to evaluate the therapeutic efficacy of
Aloe vera-coated curcumin encapsulated nanoparticles in mitigating Alzheimer's disease …