Extracellular vesicles in kidney disease
C Grange, B Bussolati - Nature Reviews Nephrology, 2022 - nature.com
Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …
They function as a long-distance cell-to-cell communication mechanism that modulates the …
Mesenchymal stem cells and exosome therapy for COVID-19: current status and future perspective
A Gupta, S Kashte, M Gupta, HC Rodriguez… - Human cell, 2020 - Springer
Acute respiratory distress syndrome (ARDS) is the main cause for the COVID-19 infection-
related morbidity and mortality. Recent clinical evidences suggest increased level of …
related morbidity and mortality. Recent clinical evidences suggest increased level of …
Differential therapeutic effect of extracellular vesicles derived by bone marrow and adipose mesenchymal stem cells on wound healing of diabetic ulcers and …
Extracellular vesicles (EVs) derived from mesenchymal stem cells isolated from both bone
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury
L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
Extracellular vesicles in organ fibrosis: mechanisms, therapies, and diagnostics
DR Brigstock - Cells, 2021 - mdpi.com
Fibrosis is the unrelenting deposition of excessively large amounts of insoluble interstitial
collagen due to profound matrigenic activities of wound-associated myofibroblasts during …
collagen due to profound matrigenic activities of wound-associated myofibroblasts during …
Mesenchymal stem cells and extracellular vesicles in therapy against kidney diseases
Y Huang, L Yang - Stem cell research & therapy, 2021 - Springer
Kidney diseases pose a threat to human health due to their rising incidence and fatality rate.
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …
[HTML][HTML] Extracellular vesicles derived from patients with antibody-mediated rejection induce tubular senescence and endothelial to mesenchymal transition in renal …
Extracellular vesicles (EV) are emerging mediators in several diseases. However, their role
in the pathophysiology of antibody-mediated allograft rejection (AMR) has been poorly …
in the pathophysiology of antibody-mediated allograft rejection (AMR) has been poorly …
Tissue regeneration capacity of extracellular vesicles isolated from bone marrow-derived and adipose-derived mesenchymal stromal/stem cells
Mesenchymal stem cell (MSC)-based therapies have demonstrated tissue repair and
regeneration capacity in various preclinical models. These therapeutic effects have recently …
regeneration capacity in various preclinical models. These therapeutic effects have recently …
Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance
J Huang, Y Kong, C Xie, L Zhou - Stem Cell Research & Therapy, 2021 - Springer
Renal failure has a high prevalence and is becoming a public health problem worldwide.
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …
Clinical prospect of mesenchymal stromal/stem cell-derived extracellular vesicles in kidney disease: Challenges and the way forward
M Kosanović, B Milutinović, TJ Kutzner, Y Mouloud… - Pharmaceutics, 2023 - mdpi.com
Kidney disease is a growing public health problem worldwide, including both acute and
chronic forms. Existing therapies for kidney disease target various pathogenic mechanisms; …
chronic forms. Existing therapies for kidney disease target various pathogenic mechanisms; …