Background: An ENDO-European Reference Network (ERN) initiative was launched that
was endorsed by the European Society for Pediatric Endocrinology and the European …

Thyroid hormone has important effects on almost every organ system and plays a crucial
role in normal growth and neurologic development. Congenital hypothyroidism affects …

Thyroid hormone has important physiologic functions in nearly every organ system. The
critical role of thyroid hormone in growth and in physical and neurologic development lends …

Background Congenital hypothyroidism causes intellectual delay unless identified and
effectively treated soon after birth. Newborn screening has almost eliminated intellectual …

Prompt identification and adequate treatment of patients with congenital hypothyroidism is
critical to optimize outcomes. New information continues to accumulate about how to …

The evaluation and management of hypothyroidism in children are similar to adults, but
there are important differences based on the dependence on normal thyroid function for …

Context The optimal levothyroxine (LT4) dose to treat congenital hypothyroidism (CH)
remains unclear, with debate over whether higher starting doses (> 10 µg/kg) are necessary …

Objective To determine if newborn screening (NBS) programs for congenital hypothyroidism
in the US use thyroid-stimulating hormone (TSH) cutoffs that are age adjusted to account for …

Thyroid hormones (THs) are instrumental in promoting the molecular mechanisms which
underlie the complex nature of neural development and function within the central nervous …

Background and Objective: Maternal iodine nutrition and thyroid status may influence
neurocognitive development in offspring. This study investigated the effects on the …